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腹腔镜减重手术在青少年中的应用:早期和五年的临床及实验室评估。

LAPAROSCOPIC BARIATRIC SURGERY IN ADOLESCENTS: EARLY AND FIVE- YEAR CLINICAL AND LABORATORY ASSESSMENT.

机构信息

Hospital São José do Avaí, Surgery Unit - Itaperuna (RJ), Brazil.

Santa Casa de Misericórdia - Belo Horizonte (BH), Brazil.

出版信息

Arq Bras Cir Dig. 2023 Jul 17;36:e1748. doi: 10.1590/0102-672020230030e1748. eCollection 2023.

DOI:10.1590/0102-672020230030e1748
PMID:37466568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10356000/
Abstract

BACKGROUND

Obesity has reached epidemic proportions among adolescents. Methods, such as bariatric surgery, have become the most effective treatment for patients with classes III and IV obesity.

AIM

To evaluate weight loss, comorbidity remission, and long-term results of bariatric surgery in adolescents.

METHODS

Study with adolescent patients undergoing bariatric surgery, evaluating laboratory tests, comorbidities, and the percentage of excess weight loss in the preoperative period and at one, two, and five years postoperatively.

RESULTS

A total of 65 patients who met the inclusion criteria, with a mean age of 18.6 years, were included in the analysis. In the preoperative period, 30.8% of hypercholesterolemia, 23.1% of systemic arterial hypertension, and 18.4% of type 2 diabetes were recorded, with remission of these percentages occurring in 60, 66.7 and 83.4%, respectively. The mean percentage of excess weight loss was 63.48% after one year of surgery, 64.75% after two years, and 57.28% after five years. The mean preoperative total cholesterol level was 180.26 mg/dL, and after one, two, and five years, it was 156.89 mg/dL, 161.39 mg/dL, and 150.97 mg/dL, respectively. The initial mean of low-density lipoprotein was 102.19mg/dL and after five years the mean value reduced to 81.81 mg/dL. The mean preoperative glycemia was 85.08 mg/dL and reduced to 79.13 mg/dL after one year, and to 76.19 mg/dL after five years.

CONCLUSIONS

Bariatric surgery is safe and effective in adolescents, with low morbidity, resulting in a loss of excess weight and long-term stability, improving laboratory tests, and leading to remission of comorbidities, such as diabetes mellitus, hypercholesterolemia, and systemic arterial hypertension.

摘要

背景

肥胖在青少年中已达到流行程度。减重手术等方法已成为治疗 III 类和 IV 类肥胖患者的最有效手段。

目的

评估青少年减重手术的减重效果、合并症缓解情况和长期结果。

方法

对接受减重手术的青少年患者进行研究,评估实验室检查、合并症以及术前和术后 1、2 和 5 年的超重体重减轻百分比。

结果

共纳入符合纳入标准的 65 例患者,平均年龄为 18.6 岁。术前,记录到 30.8%的高胆固醇血症、23.1%的系统性动脉高血压和 18.4%的 2 型糖尿病,这些百分比分别在 60%、66.7%和 83.4%的患者中得到缓解。术后 1 年、2 年和 5 年时,超重体重减轻的平均百分比分别为 63.48%、64.75%和 57.28%。术前总胆固醇平均水平为 180.26mg/dL,术后 1 年、2 年和 5 年分别为 156.89mg/dL、161.39mg/dL 和 150.97mg/dL。初始低密度脂蛋白平均水平为 102.19mg/dL,5 年后平均水平降至 81.81mg/dL。术前平均血糖水平为 85.08mg/dL,术后 1 年降至 79.13mg/dL,术后 5 年降至 76.19mg/dL。

结论

青少年减重手术安全有效,发病率低,可减轻超重体重,长期稳定,改善实验室检查,并使糖尿病、高胆固醇血症和系统性动脉高血压等合并症得到缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8ed/10356000/02477d30faec/0102-6720-abcd-36-e1748-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8ed/10356000/02477d30faec/0102-6720-abcd-36-e1748-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8ed/10356000/02477d30faec/0102-6720-abcd-36-e1748-gf01.jpg

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本文引用的文献

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Arq Bras Cir Dig. 2023 Mar 20;36:e1725. doi: 10.1590/0102-672020230002e1725. eCollection 2023.
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REPERCUSSIONS OF BARIATRIC SURGERY ON METABOLIC PARAMETERS: EXPERIENCE OF 15-YEAR FOLLOW-UP IN A HOSPITAL IN MACEIÓ, BRAZIL.减重手术对代谢参数的影响:巴西马塞约医院 15 年随访经验。
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Pediatrics. 2019 Dec;144(6). doi: 10.1542/peds.2019-3223. Epub 2019 Oct 27.
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Laparoscopic Sleeve Gastrectomy for Adolescents Under 18 Years Old with Severe Obesity.腹腔镜袖状胃切除术治疗 18 岁以下重度肥胖青少年。
Obes Surg. 2020 Jan;30(1):267-273. doi: 10.1007/s11695-019-04150-6.
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ASMBS pediatric metabolic and bariatric surgery guidelines, 2018.美国代谢与减肥外科学会儿科代谢与减重手术指南,2018 年。
Surg Obes Relat Dis. 2018 Jul;14(7):882-901. doi: 10.1016/j.soard.2018.03.019. Epub 2018 Mar 23.
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