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增强视网膜精细血管分割:形态重建和双阈值滤波策略。

Enhancing fine retinal vessel segmentation: Morphological reconstruction and double thresholds filtering strategy.

机构信息

Nautical Science Deptartment, Faculty of Maritime, King Abdul Aziz University, Jeddah, Saudia Arabia.

Department of Electronic Engineering, Quaid-e-Awam University of Engineering, Science and Technology Larkana Campus, Sukkur, Pakistan.

出版信息

PLoS One. 2023 Jul 19;18(7):e0288792. doi: 10.1371/journal.pone.0288792. eCollection 2023.

DOI:10.1371/journal.pone.0288792
PMID:37467245
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10355391/
Abstract

Eye diseases such as diabetic retinopathy are progressive with various changes in the retinal vessels, and it is difficult to analyze the disease for future treatment. There are many computerized algorithms implemented for retinal vessel segmentation, but the tiny vessels drop off, impacting the performance of the overall algorithms. This research work contains the new image processing techniques such as enhancement filters, coherence filters and binary thresholding techniques to handle the different color retinal fundus image problems to achieve a vessel image that is well-segmented, and the proposed algorithm has improved performance over existing work. Our developed technique incorporates morphological techniques to address the center light reflex issue. Additionally, to effectively resolve the problem of insufficient and varying contrast, our developed technique employs homomorphic methods and Wiener filtering. Coherent filters are used to address the coherence issue of the retina vessels, and then a double thresholding technique is applied with image reconstruction to achieve a correctly segmented vessel image. The results of our developed technique were evaluated using the STARE and DRIVE datasets and it achieves an accuracy of about 0.96 and a sensitivity of 0.81. The performance obtained from our proposed method proved the capability of the method which can be used by ophthalmology experts to diagnose ocular abnormalities and recommended for further treatment.

摘要

眼部疾病,如糖尿病性视网膜病变,是渐进性的,视网膜血管会发生各种变化,因此难以分析疾病以进行未来治疗。已经有许多用于视网膜血管分割的计算机化算法,但细小血管会脱落,影响整体算法的性能。这项研究工作包含了新的图像处理技术,如增强滤波器、相干滤波器和二值化阈值技术,以处理不同颜色眼底图像的问题,从而实现分割良好的血管图像,并且所提出的算法在性能上优于现有工作。我们开发的技术结合了形态学技术来解决中心光反射问题。此外,为了有效地解决对比度不足和变化的问题,我们开发的技术采用了同态方法和维纳滤波。相干滤波器用于解决视网膜血管的相干性问题,然后应用双阈值技术和图像重建来实现正确分割的血管图像。我们开发的技术的结果使用 STARE 和 DRIVE 数据集进行了评估,其准确率约为 0.96,灵敏度为 0.81。从我们提出的方法中获得的性能证明了该方法的能力,该方法可以由眼科专家用于诊断眼部异常并推荐进一步治疗。

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Neural Netw. 2023 Aug;165:310-320. doi: 10.1016/j.neunet.2023.05.029. Epub 2023 Jun 2.
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Recent trends and advances in fundus image analysis: A review.眼底图像分析的最新趋势和进展:综述。
Comput Biol Med. 2022 Dec;151(Pt A):106277. doi: 10.1016/j.compbiomed.2022.106277. Epub 2022 Nov 2.
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Prompt Deep Light-Weight Vessel Segmentation Network (PLVS-Net).Prompt深度轻量级血管分割网络(PLVS-Net)。
基于特征驱动模块化神经网络的蚱蜢优化算法的混合模型用于使用眼底图像进行糖尿病视网膜病变分类
Med Biol Eng Comput. 2025 Mar 6. doi: 10.1007/s11517-025-03307-z.
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Multi-label deep learning for comprehensive optic nerve head segmentation through data of fundus images.通过眼底图像数据进行多标签深度学习以实现全面的视神经乳头分割
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Diagnosis of Multiple Sclerosis Disease in Brain Magnetic Resonance Imaging Based on the Harris Hawks Optimization Algorithm.基于哈里斯鹰优化算法的脑磁共振成像多发性硬化症诊断。
Biomed Res Int. 2021 Dec 27;2021:3248834. doi: 10.1155/2021/3248834. eCollection 2021.
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Towards Automated Eye Diagnosis: An Improved Retinal Vessel Segmentation Framework Using Ensemble Block Matching 3D Filter.迈向自动化眼部诊断:一种使用集成块匹配3D滤波器的改进视网膜血管分割框架。
Diagnostics (Basel). 2021 Jan 12;11(1):114. doi: 10.3390/diagnostics11010114.
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A review of machine learning methods for retinal blood vessel segmentation and artery/vein classification.机器学习方法在视网膜血管分割和动静脉分类中的研究进展综述。
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Retinal fundus image enhancement with image decomposition and visual adaptation.基于图像分解与视觉适应的眼底图像增强
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Robust Retinal Vessel Segmentation via Locally Adaptive Derivative Frames in Orientation Scores.基于方向得分的局部自适应导数帧稳健视网膜血管分割。
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