Al Ibrahim Eye Hospital, Isra Postgraduate Institute of Ophthalmology, Karachi, Pakistan.
Bahria University Medical and Dental College, Karachi, Pakistan.
J Pak Med Assoc. 2023 Jul;73(7):1453-1456. doi: 10.47391/JPMA.8001.
To evaluate the frequencies of ocular comorbidities among patients with type II diabetes, and the association with multiple systemic factors.
The retrospective, cross-sectional study was conducted at the Al Ibrahim Eye Hospital, Karachi, and comprised diabetic eye clinic data from April 2014 to February 2022. Demographic, biochemical and ophthalmic findings of the patients were recorded. Ocular findings analysed were best-corrected visual acuity, lens status, corneal changes, optic disc assessment, intraocular pressure and signs of retinopathy and its grading. Data was analysed using SPSS 22.
Of the 43,723 subjects, 22,677(51.86%) were males and 21,046(48.13%). The overall mean age was 54.14±10.68 years. There were 21,680(49.58%) patients with diabetes duration 5-10 years. Overall, 33,876(77.5%), had some ocular morbidity, while 9,847(22.5%) had no such complaints. The commonest morbidity was cataract12,607(28.8%), followed by refractive errors 8,508(19.5%), vision-threatening diabetic retinopathy 2,553(5.83%) and suspected glaucoma 1,211(2.76%). Vision 28 threatening diabetic retinopathy and suspected glaucoma represented sustained blindness risk 3,764(8.6%). Increasing levels of low-density lipoprotein were significantly associated with advanced diabetic eye disease and clinically significant macular oedema (p<0.05), while glycated haemoglobin >6.4 was associated significantly with diabetic retinopathy and suspected glaucoma (p<0.05).
Diabetes caused some or the other ocular morbidity that needed intervention. Poor control of biochemical parameters was seen to increase frequency of ocular complications.
评估 2 型糖尿病患者眼部合并症的频率，并评估其与多种全身因素的关系。
这是一项回顾性、横断面研究，在卡拉奇的 Al Ibrahim 眼科医院进行，纳入了 2014 年 4 月至 2022 年 2 月的糖尿病眼病诊所数据。记录患者的人口统计学、生化和眼科检查结果。分析的眼部发现包括最佳矫正视力、晶状体状况、角膜变化、视盘评估、眼内压以及视网膜病变及其分级的迹象。数据使用 SPSS 22 进行分析。
在 43723 名受试者中，22677 名（51.86%）为男性，21046 名（48.13%）为女性。总体平均年龄为 54.14±10.68 岁。21680 名（49.58%）患者的糖尿病病程为 5-10 年。总体而言，33876 名（77.5%）患者存在某种眼部疾病，9847 名（22.5%）患者无此类投诉。最常见的疾病是白内障 12607 例（28.8%），其次是屈光不正 8508 例（19.5%），威胁视力的糖尿病视网膜病变 2553 例（5.83%）和疑似青光眼 1211 例（2.76%）。威胁视力的糖尿病视网膜病变和疑似青光眼分别代表 3764 例（8.6%）持续失明风险。低密度脂蛋白水平升高与糖尿病眼病和临床显著黄斑水肿显著相关（p<0.05），而糖化血红蛋白>6.4 与糖尿病视网膜病变和疑似青光眼显著相关（p<0.05）。
糖尿病引起了某种眼部疾病，需要进行干预。生化参数控制不佳，眼部并发症的频率增加。
