The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Hangzhou, Zhejiang, China.
Institute of Basic Medicine and Cancer (IBMC), Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
J Appl Clin Med Phys. 2023 Nov;24(11):e14096. doi: 10.1002/acm2.14096. Epub 2023 Jul 19.
To study the improved rotational robustness by using joint learning of spatially-correlated organ segmentation (SCOS) for thoracic organ delineation. The network structure is not our point.
The SCOS was implemented in a U-net-like model (abbr. SCOS-net) and evaluated on unseen rotated test sets. Two hundred sixty-seven patients with thoracic tumors (232 without rotation and 35 with rotation) were enrolled. The training and validation images came from 61 randomly chosen unrotated patients. The test data included two sets. One consisted of 3000 slices from the rest 171 unrotated patients. They were rotated by us by -30°∼30°. One was the images from the 35 rotated patients. The lung, heart, and spinal cord were delineated by experienced radiation oncologists and regarded as ground truth. The SCOS-net was compared with its single-task learning counterparts, two published multiple learning task settings, and rotation augmentation. Dice, 3 distance metrics (maximum and 95th percentile of Hausdorff distances and average surface distance (ASD)) and the number of cases where ASD = infinity were adopted. We analyzed the results using visualization techniques.
In terms of no augmentation, the SCOS-net achieves the best lung and spinal cord segmentations and comparable heart delineation. With augmentation, SCOS performs better in some cases.
The proposed SCOS can improve rotational robustness, and is promising in clinical applications for its low network capacity and computational cost.
研究通过联合学习空间相关器官分割(SCOS)提高对胸部器官勾画的旋转鲁棒性。我们的重点不是网络结构。
SCOS 是在类似于 U 型网络的模型中实现的(简称 SCOS-net),并在未见过的旋转测试集中进行了评估。共纳入 267 例胸部肿瘤患者(232 例无旋转,35 例有旋转)。训练和验证图像来自 61 名随机选择的未旋转患者。测试数据包括两组。一组由其余 171 名未旋转患者的 3000 个切片组成。我们将其分别旋转-30°∼30°。另一个是来自 35 个旋转患者的图像。由经验丰富的放射肿瘤学家对肺、心脏和脊髓进行勾画,并作为金标准。将 SCOS-net 与它的单任务学习对照、两个已发表的多任务学习设置和旋转增强进行比较。采用 Dice、3 种距离度量(最大和 95 百分位 Hausdorff 距离和平均表面距离(ASD))以及 ASD=无穷大的病例数。我们使用可视化技术分析结果。
在没有增强的情况下,SCOS-net 实现了最佳的肺和脊髓分割,以及可比的心脏勾画。在增强的情况下,SCOS 在某些情况下表现更好。
所提出的 SCOS 可以提高旋转鲁棒性,并且由于其网络容量和计算成本低,在临床应用中具有很大的潜力。