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一例人乳头瘤病毒四价疫苗接种后发生的急性播散性脑脊髓炎

A case of acute disseminated encephalomyelitis following human papillomavirus quadrivalent vaccination.

作者信息

Lee Mina, Ahn Moo-Young, Roh Hakjae

机构信息

Department of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University School of Medicine, Seoul, Korea.

出版信息

Encephalitis. 2022 Apr;2(2):54-57. doi: 10.47936/encephalitis.2021.00136. Epub 2022 Jan 4.

DOI:10.47936/encephalitis.2021.00136
PMID:37469650
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10295913/
Abstract

Acute disseminated encephalomyelitis is a rare autoimmune demyelinating disease associated with preceding infection or vaccination. Herein, we report a case of refractory fulminant acute disseminated encephalomyelitis that occurred 25 days after Gardasil vaccination (Merck).

摘要

急性播散性脑脊髓炎是一种罕见的自身免疫性脱髓鞘疾病，与先前的感染或疫苗接种有关。在此，我们报告一例在接种加德西疫苗（默克公司生产）25天后发生的难治性暴发性急性播散性脑脊髓炎病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/3c0018cc76f8/encephalitis-2021-00136f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/c6e9f44f563f/encephalitis-2021-00136f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/257914d8ac19/encephalitis-2021-00136f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/3c0018cc76f8/encephalitis-2021-00136f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/c6e9f44f563f/encephalitis-2021-00136f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/257914d8ac19/encephalitis-2021-00136f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/47fd/10295913/3c0018cc76f8/encephalitis-2021-00136f3.jpg

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本文引用的文献

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Two Cases of Acute Disseminated Encephalomyelitis Following Vaccination Against Human Papilloma Virus.两例接种人乳头瘤病毒疫苗后发生的急性播散性脑脊髓炎
Intern Med. 2016;55(21):3181-3184. doi: 10.2169/internalmedicine.55.5472. Epub 2016 Nov 1.
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Acute Disseminated Encephalomyelitis Following Immunization with Human Papillomavirus Vaccines.人乳头瘤病毒疫苗免疫接种后发生的急性播散性脑脊髓炎
Intern Med. 2016;55(21):3077-3078. doi: 10.2169/internalmedicine.55.7217. Epub 2016 Nov 1.
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Refractory Fulminant Acute Disseminated Encephalomyelitis (ADEM) in an Adult.
成人难治性暴发性急性播散性脑脊髓炎（ADEM）
Front Neurol. 2014 Dec 23;5:270. doi: 10.3389/fneur.2014.00270. eCollection 2014.
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Acute disseminated encephalomyelitis following vaccination against human papilloma virus.接种人乳头瘤病毒疫苗后发生的急性播散性脑脊髓炎。
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Neurology. 2007 Apr 17;68(16 Suppl 2):S23-36. doi: 10.1212/01.wnl.0000259404.51352.7f.
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Human papillomavirus quadrivalent (types 6, 11, 16, 18) recombinant vaccine (Gardasil).人乳头瘤病毒四价（6、11、16、18型）重组疫苗（加德西）
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