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未破裂颅内动脉瘤平稳夹闭术后的后部可逆性脑病综合征:一例报告

Posterior reversible encephalopathy syndrome following uneventful clipping of an unruptured intracranial aneurysm: A case report.

作者信息

Hwang Joseph, Cho Won-Ho, Cha Seung-Heon, Ko Jun-Kyueng

机构信息

Department of Neurosurgery, Biomedical Research Institute, Pusan National University Hospital, School of Medicine, Pusan National University, Busan 49241, South Korea.

出版信息

World J Clin Cases. 2023 Jul 6;11(19):4723-4728. doi: 10.12998/wjcc.v11.i19.4723.

Abstract

BACKGROUND

Posterior reversible encephalopathy syndrome (PRES) is characterized mainly by occipital and parietal lobe involvement, which can be reversible within a few days. Herein, we report a rare case of PRES that developed after craniotomy for an unruptured intracranial aneurysm (UIA).

CASE SUMMARY

A 59-year-old man underwent clipping surgery for the treatment of UIA arising from the left middle cerebral artery. Clipping surgery was performed uneventfully, and he regained consciousness quickly immediately after the surgery. At the 4th hour after surgery, he developed a disorder of consciousness and aphasia. Magnetic resonance imaging revealed cortical and subcortical T2/FLAIR hyperintensities in the parietal, occipital, and frontal lobes ipsilaterally, without restricted diffusion, consistent with unilateral PRES. With conservative treatment, his symptoms and radiological findings almost completely disappeared within weeks. In our case, the important causative factor of PRES was suspected to be a sudden increase in cerebral perfusion pressure associated with temporary M1 occlusion.

CONCLUSION

Our unique case highlights that, to our knowledge, this is the second report of PRES developing after craniotomy for the treatment of UIA. Surgeons must keep PRES in mind as one of the causes of perioperative neurological abnormality following clipping of an UIA.

摘要

背景

后部可逆性脑病综合征(PRES)主要特征为枕叶和顶叶受累,数天内可逆转。在此,我们报告1例罕见的PRES病例,该病例发生于未破裂颅内动脉瘤(UIA)开颅术后。

病例摘要

1例59岁男性因左大脑中动脉UIA行夹闭手术。夹闭手术顺利进行,术后他很快恢复意识。术后第4小时,他出现意识障碍和失语。磁共振成像显示同侧顶叶、枕叶和额叶皮质及皮质下T2/FLAIR高信号,无扩散受限,符合单侧PRES。经保守治疗,数周内其症状和影像学表现几乎完全消失。在我们的病例中,PRES的重要致病因素怀疑是与临时M1闭塞相关的脑灌注压突然升高。

结论

据我们所知,我们的独特病例突出表明,这是第2例关于UIA开颅术后发生PRES的报告。外科医生必须将PRES作为UIA夹闭术后围手术期神经功能异常的原因之一加以牢记。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff5a/10353519/84977f28cf8a/WJCC-11-4723-g001.jpg

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