Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda
Faculty of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.
BMJ Open. 2023 Jul 20;13(7):e069778. doi: 10.1136/bmjopen-2022-069778.
Quality of life (QoL) greatly influences the outcomes of patients with mental illnesses and there is evidence that there is an association between QoL and the relapse of Opioid Use Disorder (OUD). However, no reviews elucidate the relationship between QoL and the relapse of OUD. This document provides a scoping review protocol that aims to systematically chart and synthesise the published, unpublished and grey literature about the relationship between QoL and relapse of OUD.
The enhanced six-stage methodological framework for scoping reviews of Arksey and O'Malley will be used. The main research question guiding the review will be: What is the relationship between QoL and relapse of OUD? Peer-reviewed and non-peer-reviewed articles, reports, and policy documents will be eligible to be included in the review with no limits on publication date. PubMed, PsycINFO, Google Scholar, Scopus, OVID and Cochrane Library will be among the databases searched. We shall identify grey literature from Google Scholar, ProQuest database, Grey Source Index, Open Grey and OpenDOAR. The reporting of the review will follow the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Criteria for evidence inclusion and exclusion will be used during literature screening and mapping.
Patients and the public will not be involved in the interpretations of the findings, therefore, we shall not seek approval from an ethics committee. Results will be disseminated through publication in a peer-reviewed, scientific journal, conference presentations.
生活质量（QoL）极大地影响着精神疾病患者的治疗结果，有证据表明 QoL 与阿片类药物使用障碍（OUD）的复发之间存在关联。然而，目前尚无文献综述阐明 QoL 与 OUD 复发之间的关系。本文提供了一个范围综述方案，旨在系统地绘制和综合发表的、未发表的和灰色文献中关于 QoL 与 OUD 复发之间关系的文献。
将使用增强的 Arksey 和 O'Malley 六阶段方法框架进行范围综述。指导综述的主要研究问题将是：QoL 与 OUD 复发之间存在什么关系？将有资格纳入综述的包括同行评议和非同行评议的文章、报告和政策文件，对发表日期没有限制。将在 PubMed、PsycINFO、Google Scholar、Scopus、OVID 和 Cochrane Library 等数据库中搜索文献。我们将从 Google Scholar、ProQuest 数据库、灰色源索引、Open Grey 和 OpenDOAR 中确定灰色文献。综述的报告将遵循系统评价和荟萃分析扩展的首选报告项目的指南。在文献筛选和映射过程中，将使用证据纳入和排除标准。
患者和公众不会参与研究结果的解释，因此，我们不会向伦理委员会寻求批准。结果将通过发表在同行评议的科学期刊上、会议报告进行传播。
