Jacob E T, Shapira Z, Lindner A, Many M
J Urol Nephrol (Paris). 1979 Jan-Feb;85(1-2):47-54.
The repair of pre-existing bladder sphincter lesions in patients excluded from kidney transplant programs, and the recovery of grafts threatened by ureteral complications, are favourable influences in establishing equilibrium between dialysis and transplantation. In a series of 74 kidney transplants, two patients were able to receive grafts: one after the reconstruction of an ileal tube and the other after bladder diverticulectomy and resection of the bladder neck. Two other grafts, complicated by ureteral necrosis, were able to be conserved following a uretero-ureterostomy in the first case, and a psoic bladder in the second. These repair operations are discussed from three points of view: incidence, procedures, and complications. Advances made in transplanting kidneys encourage its use in patients who were previously excluded from receiving transplants because of bladder sphincter lesions. These lesions can be the cause of a renal insufficiency, or those associated with the original kidney disease. This group of patients represents 3 to 5% of the population of patients on permanent dialysis who respond to the other criteria for inclusion in the lists of potential receivers of kidney transplants: some of them could benefit from the graft if their lesions were treated by the standard urological methods. Furthermore, 5 to 8% of those with kidney transplants could lose the grafted kidney, which is immunologically tolerated, because of urological complications. As with patients in the first category, they also could obtain benefit from repair procedures on the urinary tract. A total of 74 kidney grafts were performed in the Sheba medical Center between March 1971 and July 1977: two patients were able to benefit from preventive urological procedures before transplantation: two others with grafts developed ureteral complications and were benefited by therapeutic procedures rarely used in kidney transplantation cases.
对于被排除在肾移植项目之外的患者,修复先前存在的膀胱括约肌病变,以及挽救受输尿管并发症威胁的移植物,对在透析和移植之间建立平衡具有积极影响。在一系列74例肾移植手术中,有两名患者能够接受移植:一名在回肠管重建后,另一名在膀胱憩室切除和膀胱颈切除后。另外两个移植物出现输尿管坏死并发症,第一例通过输尿管-输尿管吻合术得以保留移植物,第二例通过腰大肌膀胱术得以保留。本文从三个角度讨论这些修复手术:发生率、手术方法和并发症。肾移植技术的进步促使其应用于因膀胱括约肌病变而先前被排除在移植之外的患者。这些病变可能是肾功能不全的原因,或者与原发性肾脏疾病相关。这组患者占长期透析患者群体的3%至5%,他们符合肾移植潜在受者名单中的其他入选标准:如果通过标准泌尿外科方法治疗其病变,其中一些患者可能从移植中获益。此外,5%至8%的肾移植患者可能因泌尿系统并发症而失去免疫耐受的移植肾。与第一类患者一样,他们也可能从尿路修复手术中获益。1971年3月至1977年7月期间,舍巴医疗中心共进行了74例肾移植手术:两名患者在移植前能够受益于预防性泌尿外科手术;另外两名接受移植的患者出现输尿管并发症,并受益于肾移植病例中很少使用的治疗性手术。