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[肾移植联合皮肤可控性尿流改道术(附6例报告)]

[Kidney transplantation with cutaneous continent urinary diversion (apropos of 6 cases)].

作者信息

Maréchal J M, Dawhara M, Gelet A, Martin X, Choukair M, Sanserino R, Viguer L L, Cuzin B, Dubernard J M

机构信息

Service d'Urologie et Chirurgie de la Transplantation, Hôpital E. Herriot, Lyon, France.

出版信息

Prog Urol. 1991 Feb;1(1):110-23.

PMID:1364637
Abstract

In a series of 525 renal transplantations performed between January 1987 and September 1990, 5 patients (i.e. 1%) presented with vesical, sphincteric and urethral lesions which prevented classical uretero-vesical or uretero-ureteric reimplantation and functionally satisfactory vesico-sphincteric reconstruction. Under these conditions, in which drainage of the urine into the bladder was impossible, a diversion was created using a continent intestinal reservoir constructed prior to the graft. Four Kock pouches and one Mainz pouch were created during the months preceding renal transplantation with a cadavre kidney. A sixth patient, transplanted in 1981, had to undergo continent urinary diversion in February 1988 after a non-functional bladder augmentation for problems of bladder drainage. We did not observe any mortality or major medical or surgical complications. The follow-up after transplantation in the first 5 patients is now 3, 6, 10, 37 and 40 months. Renal function is normal in all 5 cases with serum creatinine below 130 mmol/l. For the sixth patient, the follow-up is 9 years after the transplantation and 32 months after the continent urinary diversion; serum creatinine is 200 mmol/l and stable since the urinary diversion. Continence is excellent and the comfort of all of the patients is undeniable. However, all patients present with bacteriuria with no symptomatic urinary tract infection.

摘要

在1987年1月至1990年9月间进行的525例肾移植手术中,有5例患者(即1%)出现膀胱、括约肌和尿道病变,这使得经典的输尿管膀胱或输尿管输尿管再植术以及功能良好的膀胱括约肌重建无法进行。在这种无法将尿液引流至膀胱的情况下,在移植前利用构建的可控性肠道贮尿囊进行了改道。在肾移植前的几个月里,利用尸体肾制作了4个Kock贮尿囊和1个Mainz贮尿囊。第6例患者于1981年接受移植,在1988年2月因膀胱引流问题进行了无效的膀胱扩大术后,不得不接受可控性尿流改道。我们未观察到任何死亡病例或严重的内科或外科并发症。前5例患者移植后的随访时间目前分别为3个月、6个月、10个月、37个月和40个月。所有5例患者的肾功能均正常,血清肌酐低于130 mmol/L。对于第6例患者,随访时间为移植后9年和可控性尿流改道后32个月;血清肌酐为200 mmol/L,自尿流改道后一直稳定。控尿情况极佳,所有患者的舒适度也不容置疑。然而,所有患者均有菌尿,但无有症状的尿路感染。

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