School of Chemistry and Chemical Engineering, Lanzhou Jiaotong University, Lanzhou, Gansu 730070, China.
School of Chemistry and Chemical Engineering, Lanzhou Jiaotong University, Lanzhou, Gansu 730070, China.
Spectrochim Acta A Mol Biomol Spectrosc. 2023 Dec 15;303:123159. doi: 10.1016/j.saa.2023.123159. Epub 2023 Jul 16.
A newly designed and synthesized Salamo-Salen-Salamo-Zn(II) complex sensor (sensor ZT) was extensively explored for anion sensing studies. The selectivity and sensitivity of the sensor ZT towards HPO ions were based on ICT and CHEF effects, and via displacement pathways in DMSO/HO (9:1, v/v) medium in the presence of other anions like, PO, HPO and PO in a short time, separately. The prepared ZT sensor has excellent association constant and low detection lines. The sensing mechanism and binding mode of the sensor were studied by UV-Vis spectroscopy, HR-MS, H NMR titration and theory calculations (DFT & TD-DFT) for analytes. The time response and stability of the sensor are also given. Meanwhile, the sensor ZT can be widely used as a simple and effective solid-state optical sensor to detect HPO by intuitive fluorescence changes. In addition, besides the environment can be used as a powerful instrument for detecting HPO, based on the good biocompatibility and tissue permeability of ZT, effectively monitoring HPO in cellular distribution by confocal microscopy using Zebrafish and bean sprout.
一种新设计和合成的 Salamo-Salen-Salamo-Zn(II) 配合物传感器（传感器 ZT）被广泛用于阴离子传感研究。传感器 ZT 对 HPO 离子的选择性和灵敏度基于 ICT 和 CHEF 效应，并通过在 DMSO/HO（9:1，v/v）介质中存在其他阴离子（如 PO、HPO 和 PO）时的置换途径，在短时间内分别实现。制备的 ZT 传感器具有优异的结合常数和低检测线。通过紫外-可见光谱、高分辨率质谱、1H NMR 滴定和理论计算（DFT 和 TD-DFT）研究了传感器的传感机制和结合模式。还给出了传感器的时间响应和稳定性。同时，传感器 ZT 可以广泛用作一种简单有效的固态光学传感器，通过直观的荧光变化来检测 HPO。此外，由于 ZT 具有良好的生物相容性和组织通透性，除了环境可以作为检测 HPO 的有力工具外，还可以使用斑马鱼和豆芽通过共聚焦显微镜有效地监测细胞内 HPO 的分布。
