从一线生机到生命线：拉撒路现象的范围综述。

From flatline to lifeline: A scoping review of the Lazarus phenomenon.

机构信息

Department of Emergency Medicine, Faculty of Medicine, University of Thessaly, BIOPOLIS, 41500 Larissa, Greece.

出版信息

Am J Emerg Med. 2023 Oct;72:44-57. doi: 10.1016/j.ajem.2023.07.017. Epub 2023 Jul 17.

DOI:10.1016/j.ajem.2023.07.017

PMID:37480591

Abstract

BACKGROUND

The Lazarus phenomenon or autoresuscitation (autoROSC) is the return of spontaneous circulation (ROSC) after the termination of the cardiopulmonary resuscitation (CPR) efforts.

PURPOSE

The purpose of the current scoping review is to present the available data in the literature regarding autoROSC.

METHODS

We reviewed four scientific databases to identify all studies which reported autoROSC cases in patients who underwent CPR. We then extracted all information relevant to CPR and autoROSC. The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews.

RESULTS

We identified 66 studies describing 76 autoROSC cases. The majority of cardiac arrests were in-hospital (44, 57.89%). Median time from termination of CPR to autoROSC was 5 min. Regarding the outcome, 52 (77.61%) patients died and 11 (14.47%) patients had intact neurological outcome. A higher mortality rate was identified in patients with respiratory comorbidities. Overall, 24 (31.58%) patients survived.

CONCLUSION

AutoROSC is probably an under-reported event in the medical community. Healthcare professionals should be aware of the phenomenon and actively monitor for it, when appropriate.

摘要

背景

拉撒路现象或自主复搏（autoROSC）是心肺复苏（CPR）停止后自发循环（ROSC）的恢复。

目的

本次范围综述的目的是呈现文献中关于 autoROSC 的现有数据。

方法

我们检索了四个科学数据库，以确定所有报告 CPR 患者发生 autoROSC 病例的研究。然后提取与 CPR 和 autoROSC 相关的所有信息。综述按照系统评价和荟萃分析扩展的首选报告项目进行。

结果

我们确定了 66 项描述了 76 例 autoROSC 病例的研究。大多数心脏骤停发生在院内（44 例，57.89%）。从 CPR 停止到 autoROSC 的中位数时间为 5 分钟。关于结局，52 例（77.61%）患者死亡，11 例（14.47%）患者有完整的神经功能结局。有呼吸系统合并症的患者死亡率更高。总体而言，24 例（31.58%）患者存活。