School of Biomedical Engineering & Imaging Sciences, King's College London, UK.
School of Biomedical Engineering & Imaging Sciences, King's College London, UK.
Med Image Anal. 2023 Oct;89:102793. doi: 10.1016/j.media.2023.102793. Epub 2023 Mar 22.
The diagnostic value of ultrasound images may be limited by the presence of artefacts, notably acoustic shadows, lack of contrast and localised signal dropout. Some of these artefacts are dependent on probe orientation and scan technique, with each image giving a distinct, partial view of the imaged anatomy. In this work, we propose a novel method to fuse the partially imaged fetal head anatomy, acquired from numerous views, into a single coherent 3D volume of the full anatomy. Firstly, a stream of freehand 3D US images is acquired using a single probe, capturing as many different views of the head as possible. The imaged anatomy at each time-point is then independently aligned to a canonical pose using a recurrent spatial transformer network, making our approach robust to fast fetal and probe motion. Secondly, images are fused by averaging only the most consistent and salient features from all images, producing a more detailed compounding, while minimising artefacts. We evaluated our method quantitatively and qualitatively, using image quality metrics and expert ratings, yielding state of the art performance in terms of image quality and robustness to misalignments. Being online, fast and fully automated, our method shows promise for clinical use and deployment as a real-time tool in the fetal screening clinic, where it may enable unparallelled insight into the shape and structure of the face, skull and brain.
超声图像的诊断价值可能受到伪像的限制,特别是声影、对比度不足和局部信号丢失。其中一些伪像是探头方向和扫描技术的依赖性的,每个图像都给出了所成像解剖结构的独特的、局部的视图。在这项工作中,我们提出了一种新的方法,将从多个视图采集的部分成像胎儿头部解剖结构融合到完整解剖结构的单个相干 3D 体积中。首先,使用单个探头采集一系列自由式 3D US 图像,尽可能多地捕获头部的不同视图。然后,使用递归空间变形网络将每个时间点的成像解剖结构独立地对齐到规范姿势,使我们的方法对快速的胎儿和探头运动具有鲁棒性。其次,通过仅对所有图像中最一致和最突出的特征进行平均来融合图像,从而产生更详细的复合图像,同时最小化伪像。我们使用图像质量指标和专家评分对我们的方法进行了定量和定性评估,在图像质量和对不对齐的鲁棒性方面取得了最先进的性能。由于是在线的、快速的和完全自动化的,我们的方法有望在临床中得到应用和部署,作为胎儿筛查诊所中的实时工具,它可以提供无与伦比的对面部、颅骨和大脑形状和结构的深入了解。