Baum K, Girke W, Bräu H, Schörner W, Felix R
Nervenarzt. 1986 Aug;57(8):455-60.
40 patients with a definite diagnosis and 16 patients with an initial manifestation of multiple sclerosis were investigated by cerebral nuclear magnetic resonance imaging (NMR) and compared. The initial manifestation is predominantly characterized in the NMR by significantly less periventricular involvement, especially within the region of the occipital horns, by significantly rarer appearance of confluent, periventricular lesions within the region of the pars centralis and the temporal horns of the lateral ventricles and by significantly rarer appearance of circumscribed non-periventricular lesions. Unlike those in definite multiple sclerosis, the morphology and distribution of the initial lesions do not show a stereotypical and diagnostically characteristic pattern. The importance of the cerebral NMR for the early diagnosis of multiple sclerosis lies primarily in the indication of disseminated lesions.
对40例确诊为多发性硬化症的患者及16例首发多发性硬化症的患者进行了脑核磁共振成像（NMR）检查并比较。首发症状在核磁共振成像中的主要特征为脑室周围受累明显较少，尤其是枕角区域，侧脑室中央部和颞角区域融合性脑室周围病变的出现明显较少，以及局限性非脑室周围病变的出现明显较少。与确诊的多发性硬化症患者不同，首发病变的形态和分布未显示出典型的诊断特征模式。脑核磁共振成像对多发性硬化症早期诊断的重要性主要在于提示播散性病变。
