视神经交叉胶质瘤放疗后烟雾病样血管闭塞模式
Moyamoya pattern of vascular occlusion after radiotherapy for glioma of the optic chiasm.
作者信息
Beyer R A, Paden P, Sobel D F, Flynn F G
出版信息
Neurology. 1986 Sep;36(9):1173-8. doi: 10.1212/wnl.36.9.1173.
PMID:3748382
Abstract
We studied three children who suffered massive strokes 2 to 5 years after intracranial irradiation of optic chiasm gliomas. Arteriography showed moyamoya changes in all three. CTs showed dramatic reduction in tumor size in two patients, but we believe radiotherapy should only be used sparingly to treat optic chiasm gliomas in young children, because its efficacy is unproven, and side effects may be catastrophic.
摘要
我们研究了三名儿童，他们在颅内视神经交叉胶质瘤放疗后2至5年发生了大面积中风。血管造影显示三人都有烟雾病样改变。CT显示两名患者肿瘤大小显著缩小，但我们认为放疗仅应谨慎用于治疗幼儿的视神经交叉胶质瘤，因为其疗效未经证实，且副作用可能是灾难性的。
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