Nazarpour Sima, Poursani Afshin Shokati, Simbar Masoumeh, Yarandi Razieh Bidhendi
Department of Midwifery, Faculty of Medical Sciences, Varamin-Pishva Branch, Islamic Azad University, Tehran, Iran.
Department of Chemical Engineering, Health, Safety & Environment, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
Iran J Public Health. 2023 Jun;52(6):1278-1288. doi: 10.18502/ijph.v52i6.12994.
We aimed to investigate the relationship between air pollution and the Infant mortality rate (IMR) during nearly ten years in Tehran, Iran.
This study is a retrospective cohort case using time series analysis. Air pollution monitoring data during the study period (2009-2018) were collected from the information of 23 Air Quality Control Centers in different areas of Tehran. For this purpose, the daily measures of PM10, PM2.5, O3, CO, SO2, NO2 were obtained. Data on infant mortality was obtained from the National Statistics Office of Iran and mortality registered in Tehran's main cemetery during the study period. Distributed lag linear and non-linear models were used.
A total of 23,206 infant deaths were reported during the study period. Following an increase of 10 ug/m3 in PM10 in an early day of exposure, the risk of mortality increased significantly (RR=1.003, 95%CI:1.001-1.005). There is a pick on lag 5-10 that shows a very strong and immediate effect of cold temperature which means that cold temperatures increase the risk of mortality at an early time. At cold temperate, (var=0 and lag 0) risk of infant mortality was significantly higher than reference temperature (19°C) (RR=1.1295, %CI: 1.01-1.25).
The results show the adverse effects of PM10 exposure on infant mortality in Tehran, Iran. Accordingly, a steady decline in PM10 levels in Tehran may have greater benefits in reducing the Infant mortality rate.
我们旨在调查伊朗德黑兰近十年空气污染与婴儿死亡率(IMR)之间的关系。
本研究是一项采用时间序列分析的回顾性队列病例研究。研究期间(2009 - 2018年)的空气污染监测数据来自德黑兰不同地区23个空气质量控制中心的信息。为此,获取了PM10、PM2.5、O3、CO、SO2、NO2的每日测量值。婴儿死亡率数据来自伊朗国家统计局以及研究期间在德黑兰主要公墓登记的死亡情况。使用了分布滞后线性和非线性模型。
研究期间共报告了23206例婴儿死亡。在暴露早期PM10每增加10微克/立方米,死亡风险显著增加(RR = 1.003,95%CI:1.001 - 1.005)。在滞后5 - 10天有一个峰值,显示出低温有非常强烈且即时的影响,这意味着低温在早期会增加死亡风险。在寒冷温度下(var = 0且滞后0),婴儿死亡率风险显著高于参考温度(19°C)(RR = 1.1295,%CI:1.01 - 1.25)。
结果显示在伊朗德黑兰暴露于PM10对婴儿死亡率有不利影响。因此,德黑兰PM10水平的稳步下降可能对降低婴儿死亡率有更大益处。