Liu Tao, Chen Jinxi, Wei Bin, Nie Fangfang, Zhu Guanghui
Department of General Surgery, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, China.
Department of Yongjia Jinxi Institute for Scar Repair, Zhejiang, China.
Heliyon. 2023 Jun 7;9(6):e16992. doi: 10.1016/j.heliyon.2023.e16992. eCollection 2023 Jun.
It is necessary to determine whether safety and efficacy of autologous skin tissue cells grafting for facial sunken or flat scars.
To identify autologous skin tissue cells grafting can reduce facial sunken or flat scars.
In this retrospective cross-sectional study, a total of 128 patients with scar (exclude pathological scar patients), who were receiving autologous skin tissue cells grafting therapy from January 1, 2016, to December 31, 2019.
Autologous skin tissue cells grafting.
Changes in scar severity, color changes in the scar area, infection rate and patient satisfaction.
A total of 128 patients with scar (89 females [69.5%]; mean [SD] age, 30.6 [13.12] years) received autologous skin tissue cells grafting therapy. SCAR (Scar Cosmesis Assessment and Rating), with scores ranging from 0 (best possible scar) to 15 (worst possible scar). After treatment 12 months, the mean [SD] of SCAR score went down from 9.85 [1.33] to 2.67 [1.21]. No infection was observed during treatment or recovery, and the main drawback after autologous skin tissue cells grafting is that the color recovery time is longer. The patient satisfaction 6 months after treatment was 85.2%, furthermore 12 months after treatment patient satisfaction was 94.7%.
In this study, autologous skin tissue cells grafting was safe and effective to treat facial scars. Therefore, autologous skin tissue cells grafting may be recommended as a reliable treatment for facial scar.
有必要确定自体皮肤组织细胞移植治疗面部凹陷或扁平瘢痕的安全性和有效性。
确定自体皮肤组织细胞移植能否减轻面部凹陷或扁平瘢痕。
设计、地点和参与者：在这项回顾性横断面研究中，共有128例瘢痕患者（不包括病理性瘢痕患者），他们在2016年1月1日至2019年12月31日期间接受了自体皮肤组织细胞移植治疗。
自体皮肤组织细胞移植。
瘢痕严重程度的变化、瘢痕区域的颜色变化、感染率和患者满意度。
共有128例瘢痕患者（89例女性[69.5%]；平均[标准差]年龄为30.6[13.12]岁）接受了自体皮肤组织细胞移植治疗。采用瘢痕美容评估与评分（SCAR），评分范围为0（最佳瘢痕）至15（最差瘢痕）。治疗12个月后，SCAR评分的平均[标准差]从9.85[1.33]降至2.67[1.21]。治疗或恢复期间未观察到感染，自体皮肤组织细胞移植后的主要缺点是颜色恢复时间较长。治疗6个月后患者满意度为85.2%，治疗12个月后患者满意度为94.7%。
在本研究中，自体皮肤组织细胞移植治疗面部瘢痕安全有效。因此，自体皮肤组织细胞移植可作为面部瘢痕的一种可靠治疗方法推荐。
