Alnemr Mhd Anas, Brad Bassel, Ismail Elmi Fatima, Li Lei
Department of Oral and Maxillofacial Surgery, Damascus University, Damascus, SYR.
Department of Maxillofacial Surgery/Plastic Operations, Klinikum Oldenburg, Oldenburg, DEU.
Cureus. 2024 Sep 6;16(9):e68817. doi: 10.7759/cureus.68817. eCollection 2024 Sep.
Patient's psychological and aesthetic quality is affected by the appearance of scars since atrophic scars might be caused by infections or inflammations that resulted from preoperative procedures. Non-surgical methods have recently been developed to increase patient satisfaction and improve the appearance of scars. In our understanding, there has not been much published medical research assessing how well nanofat grafting techniques work in terms of treating facial scars. With a six-month follow-up after the intervention, this research intends to provide four cases where scars in the facial area were controlled utilizing these materials. Based on the cases shown, it can be seen that following the procedure, the scar's measurements were minimized, its color and texture improved, and there was no pain or itching. Given its safety and effectiveness, autologous nanofat grafting has become one of the most important and well-liked aesthetic procedures. It has been discussed how modifying injectable nanofat using fine needles has opened up new clinical applications for rejuvenating aesthetic medicine. Additionally, it was pointed out that injectable PRF has gained attention due to its high concentration of growth factors, which help to promote healing and improve the appearance of the skin. Furthermore, it can be efficiently shared with autogenous nanofat grafts, which support and enhance the efficacy of adipose-derived stem cells (ADSCs) and improve adipocyte blood circulation. The current use of modified nanofat in the treatment of facial scars is supported by the procedure's safety and low risk of injection-site problems. The consistent efficacy of modified-nanofat injection in the management of depression-related facial scars was validated by the outcomes of patient satisfaction surveys and physician evaluations.
萎缩性瘢痕可能由术前手术引起的感染或炎症导致，患者的心理和美学质量会受到瘢痕外观的影响。最近已开发出非手术方法来提高患者满意度并改善瘢痕外观。据我们了解，目前尚未有大量已发表的医学研究评估纳米脂肪移植技术在治疗面部瘢痕方面的效果如何。本研究在干预后进行了为期六个月的随访，旨在提供四个利用这些材料控制面部瘢痕的病例。从所示病例可以看出，术后瘢痕尺寸减小，颜色和质地改善，且无疼痛或瘙痒。鉴于其安全性和有效性，自体纳米脂肪移植已成为最重要且最受欢迎的美容手术之一。文中讨论了使用细针改良可注射纳米脂肪如何为美容医学的年轻化开辟了新的临床应用。此外，还指出可注射富血小板纤维蛋白（PRF）因其高浓度的生长因子而受到关注，这些生长因子有助于促进愈合并改善皮肤外观。此外，它可以与自体纳米脂肪移植有效结合，后者支持并增强脂肪来源干细胞（ADSC）的功效，改善脂肪细胞血液循环。改良纳米脂肪目前在面部瘢痕治疗中的应用得到了该手术安全性及注射部位问题低风险的支持。患者满意度调查和医生评估的结果验证了改良纳米脂肪注射在治疗与凹陷相关的面部瘢痕方面的持续疗效。
