Bhoi Nihar R, Chandra Vipin, Johari Charu, Murdia Kshitiz
Reproductive Medicine, Indira IVF Hospital Private Limited, Udaipur, IND.
Clinical Research and Operations, Indira IVF Hospital Private Limited, Udaipur, IND.
Cureus. 2023 Jun 21;15(6):e40723. doi: 10.7759/cureus.40723. eCollection 2023 Jun.
Adolescent idiopathic premature ovarian failure (POF) is extremely rare. In such conditions, there is a defect in the process of the folliculogenesis axis leading to a hypoestrogenic state and infertility. This disorder significantly impacts a woman's prospective health, fertility, and motherhood. A case of a 24-year-old female diagnosed with adolescent idiopathic premature ovarian failure under hormone replacement therapy who visited us for fertility management is discussed here. The couple underwent in vitro fertilization (IVF) using donor oocytes resulting in a twin pregnancy. The clinical significance of premature ovarian failure and subsequent reproductive guidance is highlighted in this case report.
青少年特发性卵巢早衰（POF）极为罕见。在这种情况下，卵泡发生轴过程存在缺陷，导致雌激素缺乏状态和不孕。这种疾病会显著影响女性未来的健康、生育能力及成为母亲的可能性。本文讨论了一例24岁女性的病例，该女性在接受激素替代治疗时被诊断为青少年特发性卵巢早衰，前来寻求生育管理。这对夫妇使用供体卵母细胞进行了体外受精（IVF），结果成功怀上了双胞胎。本病例报告强调了卵巢早衰的临床意义及后续的生殖指导。
