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比较在澳常规诊疗机构就诊的冠心病和脑卒中患者的二级预防情况:一项使用全国性电子数据库的横断面研究。

Comparing secondary prevention for patients with coronary heart disease and stroke attending Australian general practices: a cross-sectional study using nationwide electronic database.

机构信息

Westmead Applied Research Centre, The University of Sydney, Sydney, New South Wales, Australia.

Department of Cardiology, Westmead Hospital, Sydney, New South Wales, Australia.

出版信息

BMJ Qual Saf. 2024 Jul 22;33(8):499-510. doi: 10.1136/bmjqs-2022-015699.

Abstract

OBJECTIVES

To compare secondary prevention care for patients with coronary heart disease (CHD) and stroke, exploring particularly the influences due to frequency and regularity of primary care visits.

SETTING

Secondary prevention for patients (≥18 years) in the National Prescription Service administrative electronic health record database collated from 458 Australian general practice sites across all states and territories.

DESIGN

Retrospective cross-sectional and panel study. Patient and care-level characteristics were compared for differing CHD/stroke diagnoses. Associations between the type of cardiovascular diagnosis and medication prescription as well as risk factor assessment were examined using multivariable logistic regression.

PARTICIPANTS

Patients with three or more general practice encounters within 2 years of their latest visit during 2016-2020.

OUTCOME MEASURES

Proportions and odds ratios (ORs) for (1) prescription of antihypertensives, antilipidaemics and antiplatelets and (2) assessment of blood pressure (BP) and low-density lipoprotein cholesterol (LDL-C) in patients with stroke only compared against those with CHD only and those with both conditions.

RESULTS

There were 111 892 patients with CHD only, 27 863 with stroke only and 9791 with both conditions. Relative to patients with CHD, patients with stroke were underprescribed antihypertensives (70.8% vs 82.8%), antilipidaemics (63.1% vs 78.7%) and antiplatelets (42.2% vs 45.7%). With sociodemographic factors, comorbidities and level of care considered as covariates, the odds of non-prescription of any recommended secondary prevention medications were higher in patients with stroke only (adjusted OR 1.37; 95% CI (1.31, 1.44)) compared with patients with CHD only. Patients with stroke only were also more likely to have neither BP nor LDL-C monitored (adjusted OR 1.26; 95% CI (1.18, 1.34)). Frequent and regular general practitioner encounters were independently associated with the prescription of secondary prevention medications (p<0.001).

CONCLUSIONS

Secondary prevention management is suboptimal in cardiovascular disease patients and worse post-stroke compared with post-CHD. More frequent and regular primary care encounters were associated with improved secondary prevention.

摘要

目的

比较冠心病(CHD)和中风患者的二级预防护理,特别探索初级保健就诊频率和规律性的影响。

设置

从澳大利亚所有州和地区的 458 个普通实践站点的国家处方服务行政电子健康记录数据库中整理出 18 岁及以上患者的二级预防。

设计

回顾性横断面和面板研究。比较不同 CHD/中风诊断的患者和护理水平特征。使用多变量逻辑回归检查心血管诊断和药物处方以及危险因素评估之间的关联。

参与者

2016-2020 年期间,在最近就诊的 2 年内有 3 次或以上普通就诊的患者。

结果

在仅患有中风的患者中,与仅患有 CHD 的患者和同时患有两种疾病的患者相比,(1)处方抗高血压药、降脂药和抗血小板药的比例和比值比(OR),以及(2)评估血压(BP)和低密度脂蛋白胆固醇(LDL-C)的比例和 OR。

结果

有 111892 例仅患有 CHD、27863 例仅患有中风和 9791 例同时患有两种疾病的患者。与患有 CHD 的患者相比,患有中风的患者抗高血压药(70.8% vs 82.8%)、降脂药(63.1% vs 78.7%)和抗血小板药(42.2% vs 45.7%)的处方率较低。考虑到社会人口因素、合并症和护理水平作为协变量,与仅患有 CHD 的患者相比,仅患有中风的患者非处方任何推荐的二级预防药物的可能性更高(调整后的 OR 1.37;95%CI(1.31,1.44))。仅患有中风的患者也更有可能没有监测血压和 LDL-C(调整后的 OR 1.26;95%CI(1.18,1.34))。频繁和定期的全科医生就诊与二级预防药物的处方独立相关(p<0.001)。

结论

与 CHD 后相比,心血管疾病患者的二级预防管理欠佳,且中风后更差。更频繁和更规律的初级保健就诊与改善二级预防有关。

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