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In chronic spontaneous urticaria soluble FcεRI is elevated and linked to atopy and chronic inducible urticaria.

作者信息

Moñino-Romero Sherezade, Kolkhir Pavel, Szépfalusi Zsolt, Schoepke Nicole, Metz Martin, Asero Riccardo, Ferrer Marta, Gimenez-Arnau Ana, Grattan Clive E H, Jakob Thilo, Konstantinou George N, Raap Ulrike, Staubach Petra, Zhang Ke, Bindslev-Jensen Carsten, Daschner Alvaro, Kinaciyan Tamar, Makris Michael, Marrouche Nadine, Schmid-Grendelmeier Peter, Sussman Gordon, Toubi Elias, Maurer Marcus, Altrichter Sabine

机构信息

Urticaria Center of Reference and Excellence (UCARE), Institute of Allergology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology, Berlin, Germany.

出版信息

Clin Transl Allergy. 2023 Jul;13(7):e12272. doi: 10.1002/clt2.12272.

DOI:10.1002/clt2.12272
PMID:37488737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10314276/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea3/10314276/10e494600b99/CLT2-13-e12272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea3/10314276/10e494600b99/CLT2-13-e12272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ea3/10314276/10e494600b99/CLT2-13-e12272-g001.jpg

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本文引用的文献

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Omalizumab versus cyclosporin-A for the treatment of chronic spontaneous urticaria: can we define better-responding endotypes?奥马珠单抗与环孢素 A 治疗慢性自发性荨麻疹：我们能否定义更好应答的表型？
An Bras Dermatol. 2022 Sep-Oct;97(5):592-600. doi: 10.1016/j.abd.2022.03.003. Epub 2022 Jul 16.
2
Total IgE as a Marker for Chronic Spontaneous Urticaria.总IgE作为慢性自发性荨麻疹的标志物。
Allergy Asthma Immunol Res. 2021 Mar;13(2):206-218. doi: 10.4168/aair.2021.13.2.206.
3
Soluble FcεRI, IgE, and tryptase as potential biomarkers of rapid desensitizations for platin IgE sensitized cancer patients.
可溶性FcεRI、IgE和类胰蛋白酶作为铂类IgE致敏癌症患者快速脱敏的潜在生物标志物。
J Allergy Clin Immunol Pract. 2020 Jun;8(6):2085-2088.e10. doi: 10.1016/j.jaip.2020.01.047. Epub 2020 Feb 4.
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Biomarkers and clinical characteristics of autoimmune chronic spontaneous urticaria: Results of the PURIST Study.自身免疫性慢性自发性荨麻疹的生物标志物和临床特征：PURIST 研究结果。
Allergy. 2019 Dec;74(12):2427-2436. doi: 10.1111/all.13949. Epub 2019 Jul 29.
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Soluble FcɛRI: A biomarker for IgE-mediated diseases.可溶性FcɛRI：一种用于IgE介导疾病的生物标志物。
Allergy. 2019 Jul;74(7):1381-1384. doi: 10.1111/all.13734. Epub 2019 Mar 11.
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The soluble isoform of human FcɛRI is an endogenous inhibitor of IgE-mediated mast cell responses.可溶性人 FcɛRI 同种型是 IgE 介导的肥大细胞反应的内源性抑制剂。
Allergy. 2019 Feb;74(2):236-245. doi: 10.1111/all.13567. Epub 2018 Nov 20.
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Serum autoreactivity predicts time to response to omalizumab therapy in chronic spontaneous urticaria.血清自身反应性可预测慢性自发性荨麻疹患者对奥马珠单抗治疗的反应时间。
J Allergy Clin Immunol. 2017 Mar;139(3):1059-1061.e1. doi: 10.1016/j.jaci.2016.07.047. Epub 2016 Nov 9.
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Autoimmune chronic spontaneous urticaria: What we know and what we do not know.自身免疫性慢性自发性荨麻疹：已知与未知。
J Allergy Clin Immunol. 2017 Jun;139(6):1772-1781.e1. doi: 10.1016/j.jaci.2016.08.050. Epub 2016 Oct 21.
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Relationships between levels of serum IgE, cell-bound IgE, and IgE-receptors on peripheral blood cells in a pediatric population.在儿科人群中，血清 IgE 水平、细胞结合 IgE 和外周血细胞膜表面 IgE 受体之间的关系。
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