Department of Emergency Medicine, University of Rochester Medical Center, Rochester, New York, USA.
Department of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA.
Addiction. 2023 Dec;118(12):2342-2351. doi: 10.1111/add.16300. Epub 2023 Jul 24.
There is little RCT evidence that brief interventions improve treatment seeking in individuals with severe alcohol use disorder (AUD) or treatment seeking reduces alcohol use. The aim was to test the efficacy of a brief intervention to increase treatment seeking in treatment naïve adults with severe AUD and measure its effects on alcohol use.
Parallel group, non-pharmacologic RCT with intervention (n = 197) and active control (n = 203) conditions, with blinded assessors conducting follow-ups at 1, 3 and 6 months.
Online recruitment in a 17-county region of upstate New York, USA.
Inclusion criteria consisted of ages ≥18 years, Alcohol Use Disorders Identification Test score ≥16, exceeds recommended limits for alcohol use and no history of AUD treatment. n = 400; 50% female; 79% white; mean age, 40.7; mean education, 14.6 years.
One-session telephone-delivered interventions: Cognitive-Behavioral Therapy for Treatment Seeking (CBT-TS; intervention), review of a National Institute on Alcohol Abuse and Alcoholism pamphlet on AUD treatment (control).
Self-report of any AUD treatment use over 3 months (primary outcome) and two standard measures of alcohol use over 6 months (secondary outcomes).
Intent-to-treat analyses were used. Assessment follow-up rates were ≥93%. Any alcohol-related treatment use over 3-month follow-up was obtained by 38 (19%) intervention participants and 36 (18%) control participants, a non-significant difference, χ [1] = 0.16, P = 0.689. Secondary analysis showed a significant interaction term between sex and intervention assignment (β = -1.197, P = 0.027). The interaction suggested CBT-TS was effective in men (22% vs 13%), although the evidence was somewhat weak (P = 0.071), and it was not effective in women (17% vs 24%).
A one-session cognitive-behavioral therapy intervention to increase treatment seeking in treatment naïve adults with severe alcohol use disorder did not increase treatment seeking.
仅有少量 RCT 证据表明，简短干预可改善重度酒精使用障碍（AUD）患者的治疗寻求行为，或治疗寻求行为可减少酒精使用。本研究旨在检验一种简短干预措施增加未经治疗的重度 AUD 成年人寻求治疗的效果，并测量其对酒精使用的影响。
平行分组、非药物 RCT，干预组（n=197）和活性对照组（n=203），盲法评估员在 1、3 和 6 个月时进行随访。
美国纽约州北部 17 个县的在线招募。
纳入标准包括年龄≥18 岁，酒精使用障碍识别测试（AUDIT）评分≥16，超过推荐的酒精使用限制且无 AUD 治疗史。n=400；50%为女性；79%为白人；平均年龄 40.7 岁；平均受教育年限 14.6 年。
单次电话传递干预：寻求治疗的认知行为治疗（CBT-TS；干预），审查国家酒精滥用和酒精中毒研究所关于 AUD 治疗的小册子（对照）。
3 个月内任何 AUD 治疗使用情况的自我报告（主要结局）和 6 个月内两项标准酒精使用测量（次要结局）。
意向治疗分析被使用。评估随访率≥93%。3 个月随访时，干预组 38 名（19%）参与者和对照组 36 名（18%）参与者接受了任何与酒精相关的治疗，差异无统计学意义，χ[1]=0.16，P=0.689。二次分析显示，性别和干预分配之间存在显著的交互项（β=-1.197，P=0.027）。交互项表明，CBT-TS 在男性中有效（22% vs 13%），尽管证据稍弱（P=0.071），但在女性中无效（17% vs 24%）。
对未经治疗的重度酒精使用障碍成年人进行一次认知行为治疗干预以增加治疗寻求，并未增加治疗寻求。
