Department of Hematology-Oncology, Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.
Dana Farber Cancer Institute, Harvard University, Cambridge, Massachusetts, USA.
CA Cancer J Clin. 2023 Nov-Dec;73(6):597-619. doi: 10.3322/caac.21807. Epub 2023 Jul 25.
Salivary gland cancers are a rare, histologically diverse group of tumors. They range from indolent to aggressive and can cause significant morbidity and mortality. Surgical resection remains the mainstay of treatment, but radiation and systemic therapy are also critical parts of the care paradigm. Given the rarity and heterogeneity of these cancers, they are best managed in a multidisciplinary program. In this review, the authors highlight standards of care as well as exciting new research for salivary gland cancers that will strive for better patient outcomes.
唾液腺癌是一组罕见的、组织学上多样化的肿瘤。它们的侵袭性从惰性到侵袭性不等,可能导致严重的发病率和死亡率。手术切除仍然是治疗的主要手段,但放疗和全身治疗也是治疗模式的重要组成部分。鉴于这些癌症的罕见性和异质性,最好在多学科项目中进行管理。在这篇综述中,作者强调了唾液腺癌的护理标准以及令人兴奋的新研究,这些研究将努力改善患者的预后。