Yin Yu-Ting, Gui Chao
Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, Wuhan, China.
Department of Head and Neck Surgery, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, Wuhan, China.
Front Oncol. 2025 Jul 28;15:1611107. doi: 10.3389/fonc.2025.1611107. eCollection 2025.
Adenoid cystic carcinoma of the larynx is rare, mainly localizing in the subglottic region. The clinical presentation is predominantly characterized by dyspnea and hoarseness. In this study, a 38-year-old woman presented symptoms that included hoarseness, wheezing, and coughing. A diagnosis of subglottic adenoid cystic carcinoma was made by laryngoscopy and biopsy and a total laryngectomy was subsequently performed. A decade after the initial surgical intervention, the tumor recurred in the local region. Consequently, a subsequent surgical procedure was undertaken, accompanied by postoperative radiotherapy. A subsequent 5-year follow-up examination revealed no evidence of local recurrence or distant metastasis. Subglottic adenoid cystic carcinoma is an uncommon malignancy. A comprehensive surgical excision can yield a favorable therapeutic outcome. In cases of recurrence, subsequent surgical intervention and postoperative supplemental radiotherapy can achieve positive results.
喉腺样囊性癌罕见,主要位于声门下区。临床表现主要以呼吸困难和声音嘶哑为特征。在本研究中,一名38岁女性出现声音嘶哑、喘息和咳嗽等症状。经喉镜检查和活检诊断为声门下腺样囊性癌,随后行全喉切除术。初次手术干预十年后,肿瘤在局部复发。因此,进行了后续手术,并辅以术后放疗。随后的5年随访检查未发现局部复发或远处转移的迹象。声门下腺样囊性癌是一种罕见的恶性肿瘤。全面的手术切除可产生良好的治疗效果。对于复发病例,后续手术干预和术后补充放疗可取得积极效果。