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《电离射线与喉癌(作者译)》

[Ionising rays and laryngeal carcinomas (author's transl)].

作者信息

Martin G, Glanz H, Kleinsasser O

出版信息

Laryngol Rhinol Otol (Stuttg). 1979 Mar;58(3):187-95.

PMID:374908
Abstract

Review of the literature and report of a new care of laryngeal cancer after irradiation of a benign lesion of the neck. These cases obviously become rare since benign lesions are no longer irradiated. Today the risk of inducing a second carcinoma by a successful irradiation of the first tumor becomes more important. A study of 109 patients, irradiated for laryngeal carcinoma and surviving with no evidence of disease for a period of at least 5 years has been performed. 8 of these patients developed a second primary in the previously irradiated area after 7-15 years. These second carcinomas are not rare if one considers that most patients with laryngeal carcinoma are 60-70 years old and therefore the life expectance on an average is low. These facts should be taken into consideration when deciding between surgical or radiation therapy in younger patients with high life expectance.

摘要

颈部良性病变放疗后喉癌新治疗方法的文献综述与病例报告。由于不再对良性病变进行放疗,此类病例显然变得罕见。如今,首次肿瘤成功放疗后诱发第二癌的风险更为突出。我们对109例接受喉癌放疗且至少5年无疾病证据存活的患者进行了研究。其中8例患者在7至15年后于先前放疗区域发生了第二原发癌。如果考虑到大多数喉癌患者年龄在60至70岁,因此平均预期寿命较低,那么这些第二癌并不罕见。在为预期寿命高的年轻患者决定手术或放疗时,应考虑到这些事实。

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