Alsubaie Abdulaziz, Alshabanat Abdulmajeed, Almizel Abdulrahman, Omair Mohammed, Alodaini Rahaf
King Saud University College of Medicine, Department of Infectious Diseases, Riyadh, Saudi Arabia.
King Saud University College of Medicine, Department of Internal Medicine, Riyadh, Saudi Arabia.
Case Rep Rheumatol. 2023 Jul 17;2023:9505383. doi: 10.1155/2023/9505383. eCollection 2023.
IgA vasculitis is a common type of vasculitis that is generally triggered by infectious causes. Vaccines have been reported as a trigger as well. Herein, we report a case of a young man who is previously healthy and who developed IgA vasculitis after the first dose of the COVID-19 mRNA vaccine Pfizer-BioNTech. The patient's symptoms were mainly skin and joint without renal or other system involvement. The patient had an excellent outcome with complete resolution after treatment with steroid tapering and azathioprine as a steroid-sparing agent over 6 months.
IgA血管炎是一种常见的血管炎类型，通常由感染因素引发。疫苗也被报道可作为触发因素。在此，我们报告一例既往健康的年轻男性，在接种第一剂辉瑞 - 生物科技公司的新冠mRNA疫苗后发生了IgA血管炎。患者的症状主要为皮肤和关节症状，无肾脏或其他系统受累。通过在6个月内逐渐减量使用类固醇并加用硫唑嘌呤作为类固醇节约剂进行治疗后，患者取得了良好的疗效，症状完全缓解。
