Packiyarajah Pavithera, Sundaresan K T, Nusair M S M
Internal Medicine, Teaching Hospital Batticaloa, Batticaloa, LKA.
Department of Clinical Sciences, Eastern University of Sri Lanka, Batticaloa, LKA.
Cureus. 2023 Jun 25;15(6):e40920. doi: 10.7759/cureus.40920. eCollection 2023 Jun.
The sensory ataxic variant of Guillain-Barre syndrome (GBS) is a rare subtype, with limited case reports available. We present the case of a previously healthy 26-year-old female university student who presented with bilateral foot numbness and unsteady gait for five days, without limb weakness. There were no signs of infection or recent history suggestive of infection. Examination revealed reduced pain and light touch sensation, as well as proprioception impairment in the bilateral distal lower limb, accompanied by an ataxic gait. Bilateral upper and lower limb power was normal. Cerebrospinal fluid (CSF) studies showed albuminocytological dissociation, while nerve conduction studies indicated unrecordable sensory responses with normal motor responses. Through a comprehensive evaluation of history, examination, and investigations, other potential differential diagnoses were excluded. Then the patient was diagnosed with a sensory ataxic variant of Guillain-Barre syndrome and treated with intravenous immunoglobulin (IVIG). Over time, the patient demonstrated gradual improvement and was able to resume her university studies four months after discharge.
吉兰-巴雷综合征（GBS）的感觉性共济失调变异型是一种罕见的亚型，现有病例报告有限。我们报告一例病例，患者为一名26岁的既往健康的女大学生，出现双侧足部麻木和步态不稳5天，无肢体无力。没有感染迹象或近期提示感染的病史。检查发现双侧下肢远端疼痛和轻触觉减退，以及本体感觉障碍，伴有共济失调步态。双侧上下肢肌力正常。脑脊液（CSF）检查显示蛋白细胞分离，而神经传导检查表明感觉反应无法记录，运动反应正常。通过对病史、检查和检查结果的综合评估，排除了其他潜在的鉴别诊断。然后该患者被诊断为吉兰-巴雷综合征的感觉性共济失调变异型，并接受静脉注射免疫球蛋白（IVIG）治疗。随着时间的推移，患者逐渐好转，出院四个月后能够恢复大学学习。
