Create Fertility Center, Toronto, Canada.
Lis Maternity and Women's Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Hum Fertil (Camb). 2023 Dec;26(6):1417-1428. doi: 10.1080/14647273.2023.2238898. Epub 2023 Jul 27.
With the growing challenge of abandoned surplus embryos in the ART arena, and the limited traction of embryo donation as a viable embryo disposition choice, it is important to better understand barriers to wider adoption of this opportunity. We aim to learn about perspectives and experience of participants in directed and non-identified embryo donation programmes. This was a longitudinal cohort survey study, of all participants in an embryo donation programme in a single university affiliated clinic between 2016 and 2020. Clinical data were extracted from counselling reports. Based on these data, non-identified online questionnaires were constructed and refined via Delphi procedure for face and content validity. Sixty-five online questionnaires were emailed between March-April 2021. Descriptive statistics, cross-tabulation, Fisher's exact test and t-test were used for analyses. Source of patient awareness, factors influencing the decision-making process, patient perspective and satisfaction were explored. The response rate was 67.2%. Most participants in the non-identified programme learned of it through their treating physicians, whereas most participants in the directed programme learned of it online. The main driver to donate across both cohorts was wanting to give others the opportunity to experience the joy of parenthood. Overall, 45% described moderate to marked difficulty in decision making related to donating their embryos, and this did not differ between cohorts. Non-identified donors reported feeling highly attached to the donated embryos more often than directed donors. Level of satisfaction was higher in the directed donation programme. Participants were more satisfied following directed than non-identified donation, and some even consider their counterparts as extended family. Our findings should be validated in various settings, and on larger samples.
随着辅助生殖技术（ART）领域中废弃过剩胚胎的挑战日益增加，以及胚胎捐赠作为可行的胚胎处理选择的吸引力有限，了解更广泛采用这一机会的障碍变得尤为重要。我们旨在了解定向和非识别胚胎捐赠计划参与者的观点和经验。这是一项纵向队列调查研究，研究对象为 2016 年至 2020 年间在一家附属大学诊所参与胚胎捐赠计划的所有参与者。临床数据从咨询报告中提取。基于这些数据，通过德尔菲程序构建和完善了非识别在线问卷，以确保其具有面部和内容效度。2021 年 3 月至 4 月期间，共发送了 65 份在线问卷。使用描述性统计、交叉表、Fisher 精确检验和 t 检验进行分析。探讨了患者意识的来源、影响决策过程的因素、患者观点和满意度。回复率为 67.2%。非识别计划中的大多数参与者是通过他们的主治医生了解该计划的，而定向计划中的大多数参与者是通过网络了解该计划的。两个队列中捐赠的主要驱动因素是希望给其他人一个体验为人父母的喜悦的机会。总体而言，45%的参与者表示在决定捐赠胚胎时感到中度至明显的困难，而且这两个队列之间没有差异。非识别供体比定向供体更频繁地报告对捐赠的胚胎有强烈的依恋感。定向捐赠计划的满意度更高。与非识别捐赠相比，参与者对定向捐赠更满意，有些人甚至将他们视为大家庭的一员。我们的发现应该在不同的环境和更大的样本中得到验证。
