Cheung D K, Stibal D, Weinberg S, Poleksic S
South Med J. 1986 Sep;79(9):1067-9. doi: 10.1097/00007611-198609000-00006.
Conventional mediastinoscopy has a small but definite morbidity and mortality. Our continuing study was done to determine whether needle aspiration during mediastinoscopy is a safe and reliable procedure. In 14 consecutive patients having mediastinoscopy, needle aspiration biopsy was also done. There was a 100% correlation between diagnosis made by needle cytology and the final diagnosis, with neither false-positive nor false-negative results. This correlation was only 75% in the forceps biopsy group. In 90% of the cases, the cytopathologist correctly identified the final cell type. There were no complications, even in cases of superior vena caval (SVC) obstructions. The distinct advantages of the technique include high specificity, better tissue sampling, immediate availability of results, reduced morbidity, expanded indications in SVC syndromes, and higher yield than conventional punch biopsies.
传统纵隔镜检查有一定但明确的发病率和死亡率。我们持续开展此项研究以确定纵隔镜检查期间的针吸活检是否为安全可靠的操作。在连续14例行纵隔镜检查的患者中，同时进行了针吸活检。针吸细胞学诊断与最终诊断之间的相关性为100%，无假阳性或假阴性结果。钳取活检组的这一相关性仅为75%。在90%的病例中，细胞病理学家正确识别了最终的细胞类型。即使在上腔静脉（SVC）梗阻的病例中也未出现并发症。该技术的明显优势包括高特异性、更好的组织采样、结果可即时获取、发病率降低、SVC综合征的适应证扩大以及比传统穿刺活检更高的诊断率。
