Medical Oncology, PD Hinduja National Hospital and Medical Research Centre, Mumbai, India.
Medicine, Northwick Park Hospital, Harrow, UK
BMJ Case Rep. 2023 Jul 27;16(7):e255134. doi: 10.1136/bcr-2023-255134.
Angiosarcoma is an incredibly rare type of malignancy, accounting for only 1%-2% of all soft-tissue sarcomas globally. It is clinically, pathologically and radiologically difficult to diagnose angiosarcoma owing to its varied presentation with little or no well-defined imaging findings.Kasabach-Merritt syndrome is also a lesser-heard entity which carries extremely poor prognosis. It is primarily seen in infants with vascular malformations and in kaposiform haemangioendothelioma. It is a condition of consumptive coagulopathy and only few of the cases have been reported so far in the adults with a background of angiosarcoma.This report presents the case of a male in his 70s who was diagnosed with metastatic angiosarcoma and experienced a complicated disease course due to Kasabach-Merritt syndrome.
血管肉瘤是一种非常罕见的恶性肿瘤，占全球所有软组织肉瘤的 1%-2%。由于其表现多样，几乎没有或没有明确的影像学发现，临床上、病理上和放射学上都很难诊断血管肉瘤。卡波西肉瘤-梅里特综合征也是一种较少见的实体，预后极差。它主要发生在伴有血管畸形的婴儿和卡波西样血管内皮细胞瘤中。这是一种消耗性凝血病的病症，到目前为止，只有少数病例在患有血管肉瘤的成年人中报道。本报告介绍了一名 70 多岁的男性患者，他被诊断患有转移性血管肉瘤，并因卡波西肉瘤-梅里特综合征而经历了复杂的疾病过程。
