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面部女性化手术术后感染的危险因素。

Risk Factors for Postsurgical Infections in Facial Feminization Surgery.

机构信息

Department of Otolaryngology, Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, 6 Weizman Street, 6423906, Tel Aviv, Israel.

The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Aesthetic Plast Surg. 2023 Oct;47(5):2130-2135. doi: 10.1007/s00266-023-03509-6. Epub 2023 Jul 27.

DOI:10.1007/s00266-023-03509-6
PMID:37500902
Abstract

BACKGROUND

Facial feminization surgical procedures are involving several surgical disciplines in multiple surgical sites and therefore may carry the risk of developing infections. Data on the development of postsurgical infection (PSI) and contributing factors in male-to-female transgender people (transwomen) undergoing facial feminization surgery are scarce. The aim of this study was to investigate the contributing factors to develop PSIs in facial feminization surgical procedures.

METHODS

Data from the medical records of 40 transwomen who underwent facial feminization surgeries in our institution between 2019 and 2021 were analyzed. The independent variables included demographic parameters (weight, body mass index, medical comorbidities and age), details of the surgical procedure (type, duration and whether another procedure had been performed concomitantly), type, dosage and route of administration of postoperative antibiotics and steroids, length of hospitalization and follow-up duration. Postsurgical infection was designated a dependent variable.

RESULTS

Five out of 40 patients (12.5%) developed PSI. The surgery of those with PSIs involved more sites, and the duration of nasal tamponade was more than four times longer than for patients who did not develop a PSI.

CONCLUSIONS

The current study revealed higher postsurgical infections rates after lengthy surgeries or when it involves several surgical facial feminization procedures. Multicenter clinical trial on a big cohort may enable better evidence-based results.

LEVEL OF EVIDENCE III

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

摘要

背景

面部女性化手术涉及多个手术部位的多个外科专业,因此可能存在发生感染的风险。关于接受面部女性化手术的跨性别女性(跨女)术后感染(PSI)的发展和相关因素的数据很少。本研究旨在调查导致面部女性化手术发生 PSI 的相关因素。

方法

分析了 2019 年至 2021 年在我院接受面部女性化手术的 40 名跨女的病历数据。自变量包括人口统计学参数(体重、体重指数、合并症和年龄)、手术细节(类型、持续时间以及是否同时进行了其他手术)、术后抗生素和类固醇的类型、剂量和给药途径、住院时间和随访时间。术后感染被指定为因变量。

结果

40 名患者中有 5 名(12.5%)发生 PSI。发生 PSI 的患者手术涉及更多部位,鼻填塞时间也比未发生 PSI 的患者长四倍多。

结论

本研究显示,长时间手术或涉及多个面部女性化手术时,术后感染率更高。对大样本量的多中心临床试验可能会得出更好的基于证据的结果。

证据水平 III:本刊要求作者为每篇文章分配一个证据级别。有关这些循证医学评级的完整描述,请参阅目录或在线作者指南 www.springer.com/00266。

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J Craniofac Surg. 2022;33(8):2502-2506. doi: 10.1097/SCS.0000000000008760. Epub 2022 Jul 26.
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Winds of Change in Antibiotic Therapy following Orthognathic Surgery.正颌手术后抗生素治疗的变化之风。
Medicina (Kaunas). 2022 Feb 10;58(2):263. doi: 10.3390/medicina58020263.
3
One dose of preoperative, intravenous, prophylactic antibiotics significantly lowers postoperative infection rate in septoplasty-a study of 772 operations.
术前静脉内给予一剂预防性抗生素可显著降低鼻中隔成形术术后感染率:一项 772 例手术的研究。
Clin Otolaryngol. 2022 Jan;47(1):174-180. doi: 10.1111/coa.13889. Epub 2021 Nov 21.
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Cardiovascular implications of gender-affirming hormone treatment in the transgender population.跨性别群体中性激素治疗的心血管影响。
Maturitas. 2019 Nov;129:45-49. doi: 10.1016/j.maturitas.2019.08.010. Epub 2019 Aug 20.
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Safety of Combined Facial Plastic Procedures Affecting Multiple Planes in a Single Setting in Facial Feminization for Transgender Patients.针对跨性别患者面部女性化在单一手术中进行影响多个平面的联合面部整形手术的安全性。
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A systematic review of latest evidence for antibiotic prophylaxis and therapy in oral and maxillofacial surgery.口腔颌面外科学中抗生素预防和治疗的最新证据的系统评价。
Infection. 2019 Aug;47(4):519-555. doi: 10.1007/s15010-019-01303-8. Epub 2019 Apr 3.
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Prolonged Operative Duration Increases Risk of Surgical Site Infections: A Systematic Review.手术时间延长增加手术部位感染风险:一项系统评价
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Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017.美国疾病预防控制中心 2017 年《手术部位感染预防指南》。
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