Ayabe Fuga, Sumita Kazutaka, Fujii Shoko, Fujita Kyohei, Miki Kazunori, Aizawa Yuki, Karakama Jun, Maehara Taketoshi, Nemoto Shigeru
Department of Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Department of Functional Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan.
J Neuroendovasc Ther. 2021;15(11):741-746. doi: 10.5797/jnet.tn.2020-0141. Epub 2021 Feb 22.
Although Onyx has made effective embolization possible in the endovascular treatment of arteriovenous malformation (AVM), its infusion requires a high level of skill and experience. The purpose of this study is to create a simulation model that will help to solve this technical issue.
Using data of 3D DSA images of a clinical case, an acrylonitrile-butadiene-styrene (ABS) resin model of the AVM was created with a 3D printer. Then, a hollow elastic model was created by applying silicone and eluting the ABS resin, which was finally connected to the human vascular model. Simulation of angiography and Onyx embolization using the model showed similar angiographic features and flow dynamics of contrast media and Onyx. During Onyx embolization, the plug and push technique could be performed as in a clinical case.
3D AVM model created with 3D printer enabled us to stimulate Onyx embolization of AVM.
尽管Onyx使动静脉畸形（AVM）的血管内治疗实现有效栓塞成为可能，但其注入需要高水平的技术和经验。本研究的目的是创建一个有助于解决这一技术问题的模拟模型。
利用一个临床病例的三维数字减影血管造影（3D DSA）图像数据，用3D打印机制作了一个AVM的丙烯腈-丁二烯-苯乙烯（ABS）树脂模型。然后，通过涂抹硅胶并洗脱ABS树脂创建了一个中空弹性模型，该模型最终与人体血管模型相连。使用该模型对血管造影和Onyx栓塞进行模拟，显示出造影剂和Onyx相似的血管造影特征和流动动力学。在Onyx栓塞过程中，可以像在临床病例中一样进行“填塞和推注”技术操作。
用3D打印机制作的三维AVM模型使我们能够模拟AVM的Onyx栓塞。
