Rajbanshi Lalit Kumar, Bajracharya Akriti, Devkota Dikshya
Department of Anesthesiology and Critical Care, Birat Medical College and Teaching Hospital, Biratnagar, Koshi, Nepal.
Indian J Crit Care Med. 2023 Jul;27(7):482-487. doi: 10.5005/jp-journals-10071-24487.
Spontaneous breathing trial (SBT) is always successful in mechanically ventilated patients. This study was conducted to assess the prediction of successful SBT and extubation of trachea by bedside lung ultrasound in mechanically ventilated patients.
This was a prospective observational study for 1 year conducted at a tertiary teaching hospital ICU on 102 patients with age more than 18 years and who were mechanically ventilated for more than 24 hours. Bedside lung ultrasound was used to assess the lung ultrasound score (LUS) and lung profiles in patients who clinically met the criteria for SBT. The LUS at the beginning of SBT and 30 minutes after SBT were used to predict the successful SBT and tracheal extubation.
Spontaneous breathing trial and tracheal extubation were successful in 73 (71.6%) and 57 (55.8%) of the patients. The AUC for lung ultrasound in predicting successful SBT at the beginning and 30 minutes of SBT were 0.781 (CI 95% 0.674-0.888, < 0.001) and 0.841 (CI 95% 0.742-0.941, < 0.001) with a cut-off value of 17.5 and 19.5, respectively. Similarly, AUC for LUS in relation to tracheal extubation was 0.786 (CI 95% 0.694-0.879, < 0.001) and 0.841(CI 95% 0.756-0.925, < 0.001) at 0 and 30 minutes. About 57.5% of the patients with A profiles tolerated successful SBT while 48.3% of the patients having C profile had failed SBT ( < 0.001). COPD, lung ultrasound, higher SOFA score, and longer duration of mechanical ventilation had a statistically significant negative correlation with successful SBT.
Lower LUS and A profiles lung ultrasound are associated with more successful weaning and tracheal extubation in mechanically ventilated patients.
Rajbanshi LK, Bajracharya A, Devkota D. Prediction of Successful Spontaneous Breathing Trial and Extubation of Trachea by Lung Ultrasound in Mechanically Ventilated Patients in Intensive Care Unit. Indian J Crit Care Med 2023;27(7):482-487.
自主呼吸试验(SBT)在机械通气患者中通常是成功的。本研究旨在评估床旁肺部超声对机械通气患者SBT成功及气管插管拔管的预测价值。
这是一项在一家三级教学医院重症监护病房进行的为期1年的前瞻性观察性研究,研究对象为102例年龄超过18岁且机械通气超过24小时的患者。对临床符合SBT标准的患者使用床旁肺部超声评估肺部超声评分(LUS)和肺部图像。SBT开始时及SBT后30分钟的LUS用于预测SBT成功及气管插管拔管情况。
73例(71.6%)患者SBT成功,57例(55.8%)患者气管插管拔管成功。SBT开始时及SBT 30分钟时肺部超声预测SBT成功的曲线下面积(AUC)分别为0.781(95%可信区间0.674 - 0.888,P < 0.001)和0.841(95%可信区间0.742 - 0.941,P < 0.001),截断值分别为17.5和19.5。同样,与气管插管拔管相关的LUS在0分钟和30分钟时的AUC分别为0.786(95%可信区间0.694 - 0.879,P < 0.001)和0.841(95%可信区间0.756 - 0.925,P < 0.001)。A类图像患者中约57.5%耐受SBT成功,而C类图像患者中48.3%的SBT失败(P < 0.001)。慢性阻塞性肺疾病(COPD)、肺部超声、较高的序贯器官衰竭评估(SOFA)评分及较长的机械通气时间与SBT成功呈统计学显著负相关。
机械通气患者中较低的LUS及A类肺部图像与更成功的撤机及气管插管拔管相关。
Rajbanshi LK, Bajracharya A, Devkota D. 重症监护病房机械通气患者肺部超声对自主呼吸试验成功及气管插管拔管的预测。《印度重症监护医学杂志》2023;27(7):482 - 487。