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犬良性皮脂腺增生的皮肤镜特征:描述、评估及观察者间一致性

Dermoscopic features of benign sebaceous proliferations in dogs: Description, assessment and inter-observer agreement.

作者信息

Scarampella Fabia, Colombo Silvia, Dehesa Alexandra, Godizzi Francesco, Cavicchini Stefano, Fabbri Elisabetta, Roccabianca Paola

机构信息

Studio Dermatologico Veterinario, Milan, Italy.

Department of Veterinary Medicine and Animal Sciences (DIVAS), Università degli Studi di Milano, Lodi, Italy.

出版信息

Vet Dermatol. 2023 Dec;34(6):597-607. doi: 10.1111/vde.13196. Epub 2023 Jul 28.

DOI:10.1111/vde.13196
PMID:37503675
Abstract

BACKGROUND

Dermoscopy is a useful, noninvasive technique also used to assess sebaceous lesions in humans. Sebaceous hyperplasia, sebaceous adenoma and sebaceous epithelioma are common cutaneous lesions in dogs; however, their dermoscopic features have not been investigated.

HYPOTHESIS/OBJECTIVES: The objectives of this study are to describe the dermoscopic features of canine sebaceous lesions and to assess the interobserver agreement on dermoscopic parameters.

ANIMALS

Thirty-four lesions excised from 17 client-owned dogs, histologically confirmed as sebaceous proliferations, were included in this study.

MATERIALS AND METHODS

Sebaceous lesions were evaluated in vivo at ×10 magnification with a handheld dermoscope. Each dermoscopic image was assessed independently by two ECVD board-certified veterinary referral clinicians and an ECVD resident.

RESULTS

Thirty sebaceous hyperplasias, two sebaceous adenomas and two sebaceous epitheliomas were included. Dermoscopically, most lesions (91%) had single or multiple, well-defined, white-yellowish structures composed of grouped ovoid areas (clods). Irregular linear and, less commonly, arborising vessels were detected at the periphery of the yellow lobular-like structures in 93% of sebaceous hyperplasias and in 50% of neoplastic lesions. Erosions were seen in 6% of sebaceous hyperplasias and 50% of neoplastic lesions. Good interobserver agreement was found for white/yellowish clods (k = 0.75), yellow scales (k = 0.83), brown/grey dots (k = 0.80), erosions (k = 0.82) and red/brownish scales/crusts (k = 0.75). There was moderate agreement for fissures (k = 0.48) and vascular pattern (k = 0.51-0.53).

CONCLUSIONS AND CLINICAL RELEVANCE

Dermoscopy represents a useful technique to assess sebaceous gland proliferations in dogs, as it is in humans.

摘要

背景

皮肤镜检查是一种有用的非侵入性技术,也用于评估人类的皮脂腺病变。皮脂腺增生、皮脂腺腺瘤和皮脂腺上皮瘤是犬类常见的皮肤病变;然而,它们的皮肤镜特征尚未得到研究。

假设/目标:本研究的目的是描述犬皮脂腺病变的皮肤镜特征,并评估观察者之间在皮肤镜参数上的一致性。

动物

本研究纳入了从17只客户拥有的犬身上切除的34个病变,经组织学证实为皮脂腺增生。

材料和方法

使用手持式皮肤镜在×10放大倍数下对皮脂腺病变进行体内评估。每张皮肤镜图像由两名欧洲兽医皮肤病学会(ECVD)认证的兽医转诊临床医生和一名ECVD住院医生独立评估。

结果

包括30个皮脂腺增生、2个皮脂腺腺瘤和2个皮脂腺上皮瘤。在皮肤镜下,大多数病变(91%)具有单个或多个界限清楚的白色至淡黄色结构,由成群的卵圆形区域(凝块)组成。在93%的皮脂腺增生和50%的肿瘤性病变中,在黄色小叶样结构的周边检测到不规则线性血管,较少见树枝状血管。6%的皮脂腺增生和50%的肿瘤性病变可见糜烂。在白色/淡黄色凝块(k = 0.75)、黄色鳞屑(k = 0.83)、棕色/灰色斑点(k = 0.80)、糜烂(k = 0.82)和红色/棕色鳞屑/痂皮(k = 0.75)方面,观察者之间的一致性良好。在裂隙(k = 0.48)和血管形态(k = 0.51 - 0.53)方面,一致性中等。

结论及临床意义

与人类一样,皮肤镜检查是评估犬皮脂腺增生的一种有用技术。

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