Zucchetti Giulia, Gamberini Giorgia, Ciappina Sabrina, Cagnazzo Celeste, Ricci Federica, Vallero Stefano, Quarello Paola, Peretta Paola, Fagioli Franca
Pediatric Oncology and Hematology Division, Regina Margherita Children's Hospital, 10126 Turin, Italy.
Section of Child and Adolescent Neuropsychiatry, Department of Public Health and Pediatric Sciences, Regina Margherita Children's Hospital, University of Turin, 10126 Turin, Italy.
Behav Sci (Basel). 2023 Jun 27;13(7):536. doi: 10.3390/bs13070536.
Children and adolescents affected by brain tumors are at risk for neuropsychological sequelae that need to be evaluated in order to plan adequate rehabilitation programs, and to support their development and recovery. This work aims to describe an innovative prospective observational study protocol for the early evaluation and monitoring over time of neuropsychological outcomes in this pediatric population. Pediatric patients aged 3-17 with a brain tumor diagnosis will be assessed through the use of a battery of Italian standardized neuropsychological tests, with good psychometric properties and age-appropiate, at three different time points of their clinical course: at diagnosis and before surgery (T0), after surgical removal and before the start of potential adjuvant therapies (T1), and at the one-year follow-up after potential adjuvant therapies (T2). This study will allow clinicians to support the neuropsychological development of these children by promoting appropriate and timely rehabilitation and educational programs from the early phases of their clinical course.
受脑肿瘤影响的儿童和青少年有出现神经心理后遗症的风险，需要进行评估，以便制定适当的康复计划，并支持他们的发育和康复。这项工作旨在描述一种创新的前瞻性观察性研究方案，用于对这一儿科人群的神经心理结果进行早期评估和长期监测。年龄在3至17岁、被诊断患有脑肿瘤的儿科患者将在其临床病程的三个不同时间点，通过使用一系列具有良好心理测量特性且适合其年龄的意大利标准化神经心理测试进行评估：诊断时及手术前（T0）、手术切除后及潜在辅助治疗开始前（T1），以及潜在辅助治疗后的一年随访时（T2）。这项研究将使临床医生能够通过在这些儿童临床病程的早期阶段促进适当且及时的康复和教育计划，来支持他们的神经心理发育。
