Service de Maladies Infectieuses et Tropicales, Hôpital Necker-Enfants Malades, Université de Paris, Assistance Publique-Hôpitaux de Paris, Paris, France.
Service de néphrologie, Hypertension, Dialyses, Transplantation, Centre, Hospitalier Régional Universitaire, Tours, France.
Transpl Infect Dis. 2023 Oct;25(5):e14108. doi: 10.1111/tid.14108. Epub 2023 Jul 28.
Aspergillus spp. is an uncommon and life-threatening cause of transplantrenal artery pseudoaneurysm after kidney transplantation.
We report the case of a 62-year-old woman who underwent kidney transplantation 10 months before and presented a 7-cm asymptomatic transplant renal artery pseudoaneurysm. Transplanted kidney and pseudoaneurysm were surgically removed in emergency. Renal graft, urine, and pseudoaneurysm cultures grew Aspergillus flavus. She recovered after 12 months of antifungal therapy.
To date 14 cases of Aspergillus spp. renal arteritis after kidney transplantation have been published, including 50% Aspergillus flavus arteritis. Vast majority were diagnosed within 90 days after transplantation (73%). Despite allograft nephrectomy and antifungal therapy, mortality rate was high (33%).
曲霉属是一种罕见且危及生命的肾移植后肾动脉假性动脉瘤的病因。
我们报告了一例 62 岁女性的病例，该患者在 10 个月前接受了肾移植，并出现了 7 厘米无症状的移植肾动脉假性动脉瘤。紧急情况下进行了移植肾和假性动脉瘤切除术。移植肾、尿液和假性动脉瘤培养出黄曲霉。经过 12 个月的抗真菌治疗后，她康复了。
迄今为止，已经发表了 14 例肾移植后曲霉属肾动脉炎的病例，其中 50%为黄曲霉属动脉炎。绝大多数在移植后 90 天内被诊断（73%）。尽管进行了同种异体肾切除术和抗真菌治疗，但死亡率仍然很高（33%）。
