Centre for Natural Products Discovery, School of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK.
MARE-Marine and Environmental Sciences Centre/ARNET-Aquatic Research Network, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal.
Mar Drugs. 2023 Jun 29;21(7):385. doi: 10.3390/md21070385.
Marine macroalgae, such as , are gaining recognition in the cosmetics industry as valuable sources of natural bioactive compounds. This study aimed to investigate the biochemical profile of and evaluate its potential as a cosmetic ingredient. Fourier-transform infrared (FTIR), gas chromatography-mass spectrometry (GCMS), and high-resolution liquid chromatography-mass spectrometry quadrupole time-of-flight (HRLCMS QTOF) analyses were employed to assess the functional groups, phycocompounds, and beneficial compounds present in . Pigment estimation, total phenol and protein content determination, DPPH antioxidant analysis, and tyrosinase inhibition assay were conducted to evaluate the extracts' ability to counteract oxidative stress and address hyperpigmentation concerns. Elemental composition and amino acid quantification were determined using inductively coupled plasma atomic emission spectrometry (ICP-AES) and HRLCMS, respectively. FTIR spectroscopy confirmed diverse functional groups, including halo compounds, alcohols, esters, amines, and acids. GCMS analysis identified moisturizing, conditioning, and anti-aging compounds such as long-chain fatty alcohols, fatty esters, fatty acids, and hydrocarbon derivatives. HRLCMS QTOF analysis revealed phenolic compounds, fatty acid derivatives, peptides, terpenoids, and amino acids with antioxidant, anti-inflammatory, and skin-nourishing properties. Elemental analysis indicated varying concentrations of elements, with silicon (Si) being the most abundant and copper (Cu) being the least abundant. The total phenol content was 86.50 µg/mL, suggesting the presence of antioxidants. The total protein content was 113.72 µg/mL, indicating nourishing and rejuvenating effects. The ethanolic extract exhibited an IC value of 36.75 μg/mL in the DPPH assay, indicating significant antioxidant activity. The methanolic extract showed an IC value of 42.784 μg/mL. Furthermore, extracts demonstrated 62.14% inhibition of tyrosinase activity. This comprehensive analysis underscores the potential of as an effective cosmetic ingredient for enhancing skin health. Given the increasing use of seaweed-based bioactive components in cosmetics, further exploration of 's potential in the cosmetics industry is warranted to leverage its valuable properties.
海洋大型藻类，如 ，作为天然生物活性化合物的有价值来源，在化妆品行业中越来越受到认可。本研究旨在研究 的生化特征，并评估其作为化妆品成分的潜力。采用傅里叶变换红外（FTIR）、气相色谱-质谱联用（GCMS）和高分辨率液相色谱-质谱四极杆飞行时间（HRLCMS QTOF）分析来评估功能基团、藻类化合物和有益化合物在 中的存在。进行色素估计、总酚和蛋白质含量测定、DPPH 抗氧化分析和酪氨酸酶抑制测定，以评估提取物对抗氧化应激和解决色素沉着问题的能力。使用电感耦合等离子体原子发射光谱（ICP-AES）和 HRLCMS 分别测定元素组成和氨基酸定量。FTIR 光谱证实了多种功能基团的存在，包括卤代化合物、醇、酯、胺和酸。GCMS 分析鉴定了保湿、调理和抗衰老化合物，如长链脂肪醇、脂肪酯、脂肪酸和碳氢化合物衍生物。HRLCMS QTOF 分析揭示了具有抗氧化、抗炎和滋养皮肤特性的酚类化合物、脂肪酸衍生物、肽、萜类化合物和氨基酸。元素分析表明，元素的浓度不同，其中硅（Si）含量最丰富，铜（Cu）含量最丰富。总酚含量为 86.50µg/mL，表明存在抗氧化剂。总蛋白含量为 113.72µg/mL，表明具有滋养和 rejuvenating 作用。在 DPPH 测定中，乙醇提取物的 IC 值为 36.75µg/mL，表明具有显著的抗氧化活性。甲醇提取物的 IC 值为 42.784µg/mL。此外， 提取物对酪氨酸酶活性的抑制率为 62.14%。这项综合分析突显了 作为一种有效化妆品成分的潜力，可用于增强皮肤健康。鉴于海藻类生物活性成分在化妆品中的使用日益增加，有必要进一步探索 的潜力，以利用其有价值的特性。
Zotero 插件
