Vogel Todd R, Kruse Robin L, Kim Ryan J, Dombrovskiy Viktor Y
1 Division of Vascular Surgery, University of Missouri School of Medicine, Columbia, MO, USA.
2 Department of Family and Community Medicine, University of Missouri School of Medicine, Columbia, MO, USA.
Vasc Endovascular Surg. 2018 Jul;52(5):330-334. doi: 10.1177/1538574418764063. Epub 2018 Mar 19.
Race has been associated with inferior outcomes after multiple procedures, but the association of socioeconomic status with procedures for cerebrovascular disease is not well established.
Elective carotid artery stenting (CAS) and carotid endarterectomy (CEA) procedures were identified in the National Inpatient Sample, 2012 to 2014. Median household income was estimated from patient ZIP codes. Chi-square and multivariable logistic regression analysis evaluated outcomes, accounting for age, race, gender, comorbidities, procedure, income, insurance, and hospital characteristics.
We identified 234 825 carotid procedures (205 835 CEA and 28 990 CAS). Blacks and Hispanics were more likely to be among the lowest quartile income patients (LQIPs) compared to whites (53.5% and 38.7% vs 27.0%, respectively; P < .0002). Compared to highest income quartile patients, LQIP had lower rates of private insurance (16.3% vs 22.0%) and higher Medicaid use (4.7% vs 2.0%; all P < .0002). Lowest quartile income patients were more likely to receive CAS (odds ratio [OR] = 1.32, 95% confidence interval [CI]: 1.27-1.37), as were blacks and Hispanics (OR = 1.09, 95% CI: 1.02-1.26; OR = 1.31, 95% CI: 1.24-1.40, respectively). In multivariable regression, postoperative stroke was associated with LQIP, black race, and Hispanic ethnicity (OR = 1.16, 95% CI: 1.06-1.28; OR = 1.52, 95% CI: 1.33-1.73; OR = 1.43, 95% CI: 1.24-1.64, respectively). Subgroup analysis demonstrated that whites also had higher odds of stroke in the lower income quartile (OR = 1.2, 95% CI: 1.1-1.4). Mortality was associated with LQIP (OR = 1.6, 95% CI: 1.2-2.1), black race (OR = 1.8, 95% CI: 1.4-2.5), and CAS (OR = 1.3, 95% CI: 1.1-1.6). Length of stay in the lowest income quartile was longer than in patients with the highest income ( P < .0001).
Race was associated with increased hospital mortality, postoperative stroke, and overall complications after carotid procedures. Lower income was significantly associated with increased stroke and mortality irrespective of race. Disparate utilization and outcomes for carotid procedures are multifactorial. Efforts to reduce disparities will need to focus on race and other socioeconomic factors.
种族与多种手术后较差的预后相关,但社会经济地位与脑血管疾病手术的关联尚未明确确立。
在2012年至2014年的全国住院患者样本中确定了择期颈动脉支架置入术(CAS)和颈动脉内膜切除术(CEA)。根据患者的邮政编码估计家庭收入中位数。卡方检验和多变量逻辑回归分析评估了预后,并考虑了年龄、种族、性别、合并症、手术方式、收入、保险和医院特征。
我们确定了234825例颈动脉手术(205835例CEA和28990例CAS)。与白人相比,黑人和西班牙裔更有可能属于收入最低四分位数的患者(分别为53.5%和38.7%,而白人为27.0%;P <.0002)。与收入最高四分位数的患者相比,收入最低四分位数的患者拥有私人保险的比例较低(16.3%对22.0%),使用医疗补助的比例较高(4.7%对2.0%;所有P <.0002)。收入最低四分位数的患者更有可能接受CAS(比值比[OR]=1.32,95%置信区间[CI]:1.27 - 1.37),黑人和西班牙裔患者也是如此(OR分别为1.09,95% CI:1.02 - 1.26;OR = 1.31,95% CI:1.24 - 1.40)。在多变量回归中,术后中风与收入最低四分位数的患者、黑人种族和西班牙裔种族相关(OR分别为1.16,95% CI:1.06 - 1.28;OR = 1.52,95% CI:1.33 - 1.73;OR = 1.43,95% CI:1.24 - 1.64)。亚组分析表明,白人在收入较低四分位数时中风的几率也较高(OR = 1.2,95% CI:1.1 - 1.4)。死亡率与收入最低四分位数的患者(OR = 1.6,95% CI:1.2 - 2.1)、黑人种族(OR = 1.8,95% CI:1.4 - 2.5)和CAS(OR = 1.3,95% CI:1.1 - 1.6)相关。收入最低四分位数的患者住院时间比收入最高的患者更长(P <.0001)。
种族与颈动脉手术后医院死亡率增加、术后中风及总体并发症相关。无论种族如何,较低收入与中风和死亡率增加显著相关。颈动脉手术的不同利用率和预后是多因素的。减少差异的努力需要关注种族和其他社会经济因素。