School of Life Science and Engineering, School of Chemistry, Southwest Jiaotong University, Chengdu, 610031, People's Republic of China.
J Fluoresc. 2024 Jul;34(4):1545-1550. doi: 10.1007/s10895-023-03354-5. Epub 2023 Jul 28.
Based on the N-redox mechanism, a turn-on near-infrared fluorescence probe (SWJT-15) with cyano isophorone as skeleton was designed and synthesized for the detection of ferrous ions (Fe). The probe has a lower detection limit (83 nM) and fast response (200 s) to Fe ions. And the probe has unique selectivity and good anti-interference performance against Fe ions compared to other metal ions. Moreover, the probe has been successfully applied to imaging Fe ions in HeLa cells.
基于 N-氧化还原机制，设计并合成了以氰异佛尔酮为骨架的近红外荧光探针（SWJT-15），用于检测二价铁离子（Fe）。该探针对 Fe 离子具有较低的检测限（83 nM）和较快的响应时间（200 s）。与其他金属离子相比，该探针对 Fe 离子具有独特的选择性和良好的抗干扰性能。此外，该探针已成功应用于 HeLa 细胞中 Fe 离子的成像。
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