Ascherl R, Stemberger A, Lechner F, Plaumann L, Rupp G, Machka K, Erhardt W, Sorg K H, Blümel G
Unfallchirurgie. 1986 Jun;12(3):125-7. doi: 10.1007/BF02588391.
A compound of collagen and gentamicin was used in a controlled examination on 67 patients for the treatment of posttraumatic as well as postoperative osteomyelitis and, when applying cement-free endoprostheses, for hemostasis and local prevention of infection in the bed for implantation. Even in case of relatively high doses, the gentamicin concentration measured was only at the threshold value of detectability, due to the local application of the absorbable antibiotic compound. In most of all cases (n = 63), the healing of infection is demonstrated by clinical and radiobiological investigation.
胶原蛋白与庆大霉素的复合物用于对67例患者进行的对照试验，以治疗创伤后和术后骨髓炎，以及在应用无骨水泥假体时用于止血和局部预防植入床感染。即使使用相对高的剂量，由于可吸收抗生素复合物的局部应用，测得的庆大霉素浓度仅处于可检测性的阈值。在大多数病例（n = 63）中，临床和放射生物学检查表明感染已愈合。
