颅内脑膜瘤：28只犬的比较病理学研究

Intracranial meningioma: a comparative pathologic study of 28 dogs.

作者信息

Patnaik A K, Kay W J, Hurvitz A I

出版信息

Vet Pathol. 1986 Jul;23(4):369-73. doi: 10.1177/030098588602300404.

Abstract

Intracranial meningiomas were identified in 28 dogs based on histologic examination of tissue. The average age of the dogs was 11 years, and 83% (20/24) were 10 years old or older. German shepherd and mixed breed were most common (31% each, 8/26). Grossly, meningiomas were oval, dome-shaped and flattened masses adherent to the dura and compressing the brain. Forty-eight percent (15/26) of the tumors affected the dorsal surface of the brain, and two thirds of these were located in the anterior half. Histologically, tumor types were transitional (13), meningotheliomatous (11), angioblastic (three), and fibroblastic (one). There was direct invasion of the brain in 27% (6/22) although we observed neurologic signs and pathologic changes in 88% (23/26) and 90% (18/20) of the dogs, respectively. Intracranial meningioma can be compared and contrasted with this tumor in man and cats.

摘要

基于组织的组织学检查，在28只犬中发现了颅内脑膜瘤。这些犬的平均年龄为11岁，其中83%（20/24）为10岁及以上。德国牧羊犬和混种犬最为常见（各占31%，8/26）。大体上，脑膜瘤为椭圆形、圆顶状且扁平的肿块，附着于硬脑膜并压迫脑。48%（15/26）的肿瘤累及脑的背侧表面，其中三分之二位于前半部分。组织学上，肿瘤类型为过渡型（13例）、脑膜皮型（11例）、血管母细胞型（3例）和成纤维细胞型（1例）。27%（6/22）的病例存在脑的直接侵犯，不过我们分别在88%（23/26）和90%（18/20）的犬中观察到了神经症状和病理变化。颅内脑膜瘤可与人类和猫的这种肿瘤进行比较和对比。