Patnaik A K, Lieberman P H, Erlandson R A, Shaker E, Hurvitz A I
Vet Pathol. 1986 Jul;23(4):362-8. doi: 10.1177/030098588602300403.
Paranasal meningiomas were diagnosed in ten dogs based on gross and light microscopic examinations of tissue specimens, and, in one case, electron microscopic examination. Seven of ten dogs were female (average age was 13 years). Most dogs (7/10) had seizures on examination. Two dogs with meningioma located in the nasal cavity had nasal discharge, and one had epistaxis. Tumors originated in the nasoparanasal region (eight) and frontal region of the cranial cavity (two). The histologic types of meningioma included psammomatous (two), transitional (three), meningotheliomatous (two), fibroblastic (two), and angioblastic (one). Tumors were malignant and extended to the brain in eight cases. These tumors differed from intracranial meningiomas mainly in their more anaplastic nature and aggressive behavior.
根据组织标本的大体和光学显微镜检查，以及1例的电子显微镜检查，确诊了10只犬患有鼻旁脑膜瘤。10只犬中有7只为雌性（平均年龄13岁）。大多数犬（7/10）在检查时出现癫痫发作。2只鼻腔内有脑膜瘤的犬有鼻分泌物，1只出现鼻出血。肿瘤起源于鼻旁区域（8例）和颅腔额叶区域（2例）。脑膜瘤的组织学类型包括砂粒体型（2例）、过渡型（3例）、脑膜上皮型（2例）、纤维母细胞型（2例）和成血管细胞型（1例）。8例肿瘤为恶性并已侵犯至脑。这些肿瘤与颅内脑膜瘤的主要区别在于其更间变的性质和侵袭性。
