猪繁殖与呼吸综合征病毒NSP7蛋白的研究进展
Research Progress on Porcine Reproductive and Respiratory Syndrome Virus NSP7 Protein.
作者信息
Li Huawei, Luo Qin, Jing Huiyuan, Song Yuzhen, Kong Weili, Zhao Mengmeng, Zhu Qingge
机构信息
College of Food and Bioengineering, Henan University of Animal Husbandry and Economy, Zhengzhou 450047, China.
Department of Veterinary Medicine, School of Life Science and Engineering, Foshan University, Foshan 528000, China.
出版信息
Animals (Basel). 2023 Jul 11;13(14):2269. doi: 10.3390/ani13142269.
Porcine reproductive and respiratory syndrome (PRRS) is a highly contagious and severe infectious disease caused by the PRRS virus (PRRSV). PRRS is characterized by reproductive disorders in sows and respiratory dysfunction in pigs. Non-structural protein 7 (NSP7) is one of the most conserved functional proteins in PRRSV, and it plays an important role in viral replication and humoral immune responses in infected hosts. This review discusses the biological characteristics of NSP7 to provide theoretical support for its application in PRRS diagnosis, novel vaccine design, and therapeutic drug development.
猪繁殖与呼吸综合征（PRRS）是由猪繁殖与呼吸综合征病毒（PRRSV）引起的一种高度传染性和严重的传染病。PRRS的特征是母猪繁殖障碍和猪的呼吸功能障碍。非结构蛋白7（NSP7）是PRRSV中最保守的功能蛋白之一，它在病毒复制和感染宿主的体液免疫反应中起重要作用。本文综述了NSP7的生物学特性，为其在PRRS诊断、新型疫苗设计和治疗药物开发中的应用提供理论支持。
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