Monocular deprivation in kittens differently affects crossed and uncrossed visual pathways.

The effects of monocular deprivation (MD) on the crossed and uncrossed visual projections were studied using both electrophysiological and behavioural criteria. Our results show that Visual Evoked Potentials (VEPs) from the deprived eye (DE) in response to contrast reversing gratings are more reduced in the ipsilateral than in the contralateral cortex. This suggests a different sensitivity of the crossed and uncrossed visual pathways to MD. In the behavioural experiments comparable findings were obtained.