Arisanti Cokorda Istri Sri, Wirasuta I Made Agus Gelgel, Musfiroh Ida, Ikram Emmy Hainida Khairul, Muchtaridi Muchtaridi
Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, Indonesia.
Pharmacy Department, Faculty of Mathematic and Natural Science, Udayana University, Kampus Bukit Jimbaran, Bali 80361, Indonesia.
Foods. 2023 Jul 24;12(14):2810. doi: 10.3390/foods12142810.
This study aims to provide an overview of the compounds found in sweet potato () that contribute to its anti-diabetic activity and the mechanisms by which they act. A comprehensive literature search was conducted using electronic databases, such as PubMed, Scopus, and Science Direct, with specific search terms and Boolean operators. A total of 269 articles were initially retrieved, but after applying inclusion and exclusion criteria only 28 articles were selected for further review. Among the findings, four varieties of sweet potato were identified as having potential anti-diabetic properties. Phenolic acids, flavonols, flavanones, and anthocyanidins are responsible for the anti-diabetic activity of sweet potatoes. The anti-diabetic mechanism of sweet potatoes was determined using a combination of components with multi-target actions. The results of these studies provide evidence that is effective in the treatment of type 2 diabetes.
本研究旨在概述红薯中发现的有助于其抗糖尿病活性的化合物及其作用机制。使用电子数据库（如PubMed、Scopus和ScienceDirect），通过特定的搜索词和布尔运算符进行了全面的文献检索。最初检索到269篇文章，但在应用纳入和排除标准后，仅选择了28篇文章进行进一步审查。在这些研究结果中，四种红薯品种被确定具有潜在的抗糖尿病特性。酚酸、黄酮醇、黄烷酮和花青素是红薯抗糖尿病活性的原因。红薯的抗糖尿病机制是通过具有多靶点作用的成分组合来确定的。这些研究结果提供了证据，证明红薯对2型糖尿病的治疗有效。
