Al Mutawa Omar A, Izhari Mohammad Asrar, Alharbi Raed A, Sindi Abdulmajeed Abdulghani A, Alqarni Abdullah M, Alotaibi Foton E, Gosady Ahmed R A, Dardari Daifallah M M, Almutairi Abdulrahman M, Alshehri Mohammed, Athathi Ahmed I E
Medical Laboratory Department Southern Region Armed Forces Hospital, Khamis Mushait 62413, Saudi Arabia.
Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Al-Baha University, Al-Baha 65528, Saudi Arabia.
Diagnostics (Basel). 2023 Jul 18;13(14):2404. doi: 10.3390/diagnostics13142404.
(ubiquitous) and anemia together represent one of the growing health concerns globally. Gastroduodenal sequelae of infection are distinguished; however, for the infection and its implication in the development of anemia, iron has a significant health impact. We aimed to evaluate infection-associated anemia by employing a logistic regression analysis model. A retrospective (case-control) study design-based assessment of the associated-anemia. The study area was geo-referenced by QGIS/QuickMapServies. Descriptive and inferential statistical analyses were accomplished using the R-base-R-studio (v-4.0.2)-tidyverse. A -value < 0.05 was the statistical significance cut-off value. A ggplot2 package was used for data representation and visualization. Mean ± SD age, Hb, MCV, ferritin, and RBC for overall study participants were measured to be 44.0 ± 13.58, 13.84 ± 2.49, 83.02 ± 8.31, 59.42 ± 68.37, and 5.14 ± 0.75, respectively. Decreased levels of Hb (infected vs. uninfected: 13.26 ± 2.92 vs. 14.42 ± 1.75, < 0.001) ferritin (infected vs. uninfected: 48.11 ± 63.75 vs. 71.17 ± 71.14, < 0.001), and MCV (infected vs. uninfected: 81.29 ± 9.13 vs. and 84.82 ± 6.93, < 0.05) were measured to be associated with infection when compared with uninfected control group. Moreover, the magnitude (prevalence) of anemia (infected vs. uninfected: 78% vs. 21%, < 0.001), iron deficiency anemia (IDA) (infected vs. uninfected: 63.3% vs. 36.6%, < 0.001), and microcytic anemia (infected vs. uninfected: 71.6% vs. 46.1%, < 0.001) were significantly different among the -infected participants. The higher likelihood of developing anemia (AOR; 4.98, 95% CI; 3.089-8.308, < 0.001), IDA (AOR; 3.061, 95% CI; 2.135-4.416, < 0.001), and microcytic anemia (AOR; 3.289, 95% CI; 2.213-4.949, < 0.001) by 398%, 206.1%, and 229%, respectively, was associated with -infected. We recommend the regular monitoring of hematological parameters and eradication of infection to minimize the extra-gastric health consequences of infection.
(普遍存在的)[某种感染]与贫血共同构成了全球日益严重的健康问题之一。感染的胃十二指肠后遗症是有区别的;然而,对于[这种感染]及其在贫血发展中的影响,铁具有重大的健康影响。我们旨在通过使用逻辑回归分析模型来评估[感染]相关的贫血。基于回顾性(病例对照)研究设计对[感染]相关贫血进行评估。研究区域通过QGIS/QuickMapServies进行地理定位。使用R-base-R-studio(v-4.0.2)-tidyverse完成描述性和推断性统计分析。P值<0.05为统计显著性临界值。使用ggplot2包进行数据表示和可视化。总体研究参与者的平均±标准差年龄、血红蛋白(Hb)、平均红细胞体积(MCV)、铁蛋白和红细胞(RBC)分别测得为44.0±13.58、13.84±2.49、83.02±8.31、59.42±68.37和5.14±0.75。与未感染对照组相比,感染组的血红蛋白水平降低(感染组与未感染组:13.26±2.92 vs. 14.42±1.75,P<0.001)、铁蛋白水平降低(感染组与未感染组:48.11±63.75 vs. 71.17±71.14,P<0.001)以及平均红细胞体积降低(感染组与未感染组:81.29±9.13 vs. 84.82±6.93,P<0.05),这些均与[这种感染]相关。此外,感染参与者中贫血的发生率(感染组与未感染组:78% vs. 21%,P<0.001)、缺铁性贫血(IDA)(感染组与未感染组:63.3% vs. 36.6%,P<0.001)和小细胞性贫血(感染组与未感染组:71.6% vs. 46.1%,P<0.001)存在显著差异。感染[这种感染]导致患贫血的可能性更高(比值比[AOR];4.98,95%置信区间[CI];3.089 - 8.308,P<0.001)、患缺铁性贫血的可能性更高(AOR;3.061,95% CI;2.135 - 4.4