Bechir Edwin Sever
Faculty of Dental Medicine, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, 38 Gh. Marinescu Str., 540142 Targu Mures, Romania.
Diagnostics (Basel). 2023 Jul 22;13(14):2450. doi: 10.3390/diagnostics13142450.
The purpose of this study was to evaluate the efficiency of two therapeutic procedures clinically and microbiologically in the management of periodontally affected teeth: scaling and root planing alone and the laser-assisted new attachment procedure (LANAP). Molecular biological determinations of bacterial markers through the polymerase chain reaction (real-time PCR) method with standard PET tests (species-specific DNA probes at a time) were used for the quantification of three of the most important periodontal pathogens (, , and ). Both nonsurgical periodontal therapies were proven effective in patients with chronic periodontal disease; however, LANAP was associated with a greater reduction in pocket depth and improved clinical outcomes, associated with a significant decrease in the amount of . The clinical results included a decrease in periodontal pocket depth, bleeding on probing, and dental plaque, with LANAP having better overall outcomes than SRP alone. The use of Nd:YAG lasers in LANAP therapy is a safe and effective procedure that is well accepted by patients.
单纯龈下刮治和根面平整以及激光辅助新附着程序（LANAP）。通过聚合酶链反应（实时PCR）方法结合标准PET检测（一次使用种特异性DNA探针）对细菌标志物进行分子生物学测定，以量化三种最重要的牙周病原体（ 、 和 ）。两种非手术牙周治疗方法在慢性牙周病患者中均被证明有效；然而，LANAP与更大程度的牙周袋深度降低和更好的临床结果相关，同时 数量显著减少。临床结果包括牙周袋深度减小、探诊出血和牙菌斑减少，LANAP的总体效果优于单纯龈下刮治和根面平整。在LANAP治疗中使用钕钇铝石榴石激光是一种安全有效的程序，患者对此接受度良好。
