Kudron Elizabeth L, Deininger Kimberly M, Aquilante Christina L
Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, CO 80045, USA.
Colorado Center for Personalized Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA.
J Pers Med. 2023 Jun 21;13(7):1025. doi: 10.3390/jpm13071025.
Although the use of genomics to inform clinical care is increasing, clinicians feel underprepared to integrate personalized medicine (PM) into care decisions. The educational needs of physician residents and fellows, also known as graduate medical trainees (GMTs), have been overlooked. We administered an anonymous, web-based survey to all GMTs participating in training programs affiliated with our institution to evaluate their knowledge, skills, and attitudes toward PM. Of the 1190 GMTs contacted, 319 (26.8%) returned surveys. Most (88.4%) respondents reported receiving PM education in the past. Although the respondents agreed that knowledge of disease genetics (80.9%) or pharmacogenetics (87.1%) would likely lead to improved clinical outcomes, only 33.2% of the respondents felt sufficiently informed about PM. The respondents who had received PM education in residency and/or fellowship had significantly higher self-reported knowledge, ability, awareness, and adoption of PM than those who had not received this education ( < 0.0001, < 0.0001, < 0.0001, and < 0.01, respectively). Targeted training is needed to improve GMTs' confidence in interpreting and explaining genetic test results. The ideal timing for this education appears to be in residency and/or fellowship rather than in medical school.
尽管基因组学在临床护理中的应用日益增加，但临床医生在将个性化医疗（PM）纳入护理决策方面仍感到准备不足。医师住院医师和研究员（也称为研究生医学实习生，GMTs）的教育需求一直被忽视。我们对所有参加与我们机构相关培训项目的GMTs进行了一项基于网络的匿名调查，以评估他们对PM的知识、技能和态度。在联系的1190名GMTs中，319名（26.8%）回复了调查。大多数（88.4%）受访者报告过去接受过PM教育。尽管受访者一致认为疾病遗传学（80.9%）或药物遗传学（87.1%）知识可能会改善临床结果，但只有33.2%的受访者认为自己对PM有足够的了解。在住院医师培训和/或研究员培训中接受过PM教育的受访者在自我报告的PM知识、能力、意识和应用方面明显高于未接受过此类教育的受访者（分别为<0.0001、<0.0001、<0.0001和<0.01）。需要有针对性的培训来提高GMTs解读和解释基因检测结果的信心。这种教育的理想时机似乎是在住院医师培训和/或研究员培训期间，而不是在医学院。
