Salis Francesco, Puxeddu Benedetta, Piras Veronica, Belfiori Maristella, Marongiu Giuseppe, Capone Antonio, Mandas Antonella
Department of Medical Sciences, and Public Health, University of Cagliari, 09100 Cagliari, Italy.
Department of Medicine, Surgery, and Pharmacy, University of Sassari, 07100 Sassari, Italy.
J Pers Med. 2023 Jul 14;13(7):1138. doi: 10.3390/jpm13071138.
Nowadays, more studies deal with "OrthoGeriatrics", for the co-management of elderly patients suffering fractures, from the admission to the discharge and beyond. For the first time at Cagliari University Hospital, we introduced an orthogeriatric service, in which trained geriatricians stay in orthopedic unit alongside trained orthopedics. The primary aim of the study was to analyze the rate of death and rehospitalization in elderly femur-fractured people of 65 or more years of age, identifying possible predictive factors. The secondary aim of the study was to analyze the recovery of daily living autonomies during the months following surgery. To reach the aim, we designed a prospective study, which is currently ongoing. We evaluated femur-fractured patients aged 65 years or more with a comprehensive geriatric assessment before surgery. The most common fractures were lateral hip ones, treated with osteosynthesis. Cognitive-affective, functional, and nutritional status, mood, and comorbidities were less impaired than in the outpatient service of the same hospital devoted to frail elderly. Pain control was excellent. A significantly low delirium incidence was found. More than a third of the sample were recognized as frail (according to the Survey of Health, Ageing and Retirement in Europe-Frailty Instrument (SHARE-FI)), and over a third of the sample were identified as a moderate-high risk of hospitalization and death (according to Multidimensional Prognostic Index (MPI)). Overall mortality rate was 13.87%, and rehospitalization rate was 11.84%. Frail people were more likely to die than non-frail (HR: 5.64), and pre-frail ones (HR: 3.97); similarly, high-risk patients were more likely to die than low-risk (HR: 8.04), and moderate-risk ones (HR: 5.46). Conversely, neither SHARE-FI nor MPI predicted rehospitalization. Creatinine (OR: 2.66, = 0.003) and folate (OR: 0.75, = 0.03) levels were independently associated with death and rehospitalization, respectively. Finally, the patients did recover the lost autonomies later, 6 months after surgery. Our study demonstrated that SHARE-FI and MPI are reliable tools to predict mortality in an orthogeriatric setting, and that creatinine and folate levels should also be measured given their independent association with negative outcomes.
如今,越来越多的研究涉及“老年骨科”,用于对骨折老年患者从入院到出院及出院后的联合管理。我们在卡利亚里大学医院首次引入了老年骨科服务,训练有素的老年病医生与训练有素的骨科医生一同在骨科病房工作。本研究的主要目的是分析65岁及以上股骨骨折老年患者的死亡率和再住院率,确定可能的预测因素。该研究的次要目的是分析术后数月日常生活自理能力的恢复情况。为实现这一目标,我们设计了一项前瞻性研究,目前该研究正在进行中。我们在手术前对65岁及以上的股骨骨折患者进行了全面的老年综合评估。最常见的骨折是外侧髋部骨折,采用骨固定术治疗。与该医院为体弱老年人设立的门诊服务相比,患者的认知情感、功能和营养状况、情绪及合并症受损程度较轻。疼痛控制良好。发现谵妄发生率显著较低。超过三分之一的样本被认定为体弱(根据欧洲健康、老龄化和退休调查-体弱指数(SHARE-FI)),超过三分之一的样本被确定为住院和死亡的中高风险(根据多维预后指数(MPI))。总体死亡率为13.87%,再住院率为11.84%。体弱患者比非体弱患者(风险比:5.64)和准体弱患者(风险比:3.97)更易死亡;同样,高风险患者比低风险患者(风险比:8.04)和中风险患者(风险比:5.46)更易死亡。相反,SHARE-FI和MPI均未预测再住院情况。肌酐水平(比值比:2.66,P = 0.003)和叶酸水平(比值比:0.75,P = 0.03)分别与死亡和再住院独立相关。最后,患者在术后6个月确实恢复了丧失的自理能力。我们的研究表明,SHARE-FI和MPI是预测老年骨科环境中死亡率的可靠工具,鉴于肌酐和叶酸水平与不良结局的独立关联,也应进行测量。