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微小 RNA 作为心血管疾病诊断的潜在生物标志物。

MicroRNAs as a Potential Biomarker in the Diagnosis of Cardiovascular Diseases.

机构信息

Centre for Epidemiological Research, Faculty of Medicine, University of Ostrava, 70103 Ostrava, Czech Republic.

Department of Epidemiology and Public Health, Faculty of Medicine, University of Ostrava, 70103 Ostrava, Czech Republic.

出版信息

Medicina (Kaunas). 2023 Jul 19;59(7):1329. doi: 10.3390/medicina59071329.

Abstract

Cardiovascular diseases (CVD) are the leading cause of death in most developed countries. MicroRNAs (miRNAs) are highly investigated molecules not only in CVD but also in other diseases. Several studies on miRNAs continue to reveal novel miRNAs that may play a role in CVD, in their pathogenesis in diagnosis or prognosis, but evidence for clinical implementation is still lacking. The aim of this study is to clarify the diagnostic potential of miRNAs in some CVDs.

摘要

心血管疾病(CVD)是大多数发达国家的主要死亡原因。MicroRNAs(miRNAs)不仅在 CVD 中,而且在其他疾病中也是研究热点。关于 miRNAs 的多项研究不断揭示出可能在 CVD 及其发病机制的诊断或预后中发挥作用的新 miRNAs,但仍缺乏临床应用的证据。本研究旨在阐明 miRNAs 在某些 CVD 中的诊断潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05bd/10386031/21883741c1c3/medicina-59-01329-g001.jpg

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