Jia Qinggong, Liang Shuhua, Wang Qingxiang
School of Material Science and Engineering, Xi'an University of Technology, Xi'an 710048, China.
Xi'an Juneng Engineering Medicine Technology Co., Ltd., Xi'an 710026, China.
Materials (Basel). 2023 Jul 19;16(14):5095. doi: 10.3390/ma16145095.
In this paper, Ti-27Nb-17Ta-8Zr/HA series composite materials were prepared by spark plasma sintering (SPS) technology. The medical titanium alloy (Ti-27Nb-17Ta-8Zr) with good mechanical properties, wear resistance, and corrosion resistance was combined with the hydroxyapatite (HA) bioactive ceramic with high biological activity and bone-binding ability. Moreover, the density, microstructure evolution, metal/ceramic reaction, mechanical behavior, in vitro bioactivity, and influencing mechanisms of composite materials with different HA contents were studied. The research results indicate that all biological composite materials are composed of β-Ti solution, α-Ti, and ceramic phases (TO, CaTiO, CaO, TiP). With the increase of HA content, the compressive strength and yield strength of the composite material show a trend of first increasing, then decreasing, and then slowly increasing. After soaking in SBF artificial simulated body fluid for 5 days, the deposition of elements such as Ca and P on the surface significantly increased, while elements such as Ti, Nb, Ta, and Zr were evenly distributed in the matrix, demonstrating good in vitro mineralization ability and facilitating the attachment and growth of osteoblasts.
本文采用放电等离子烧结（SPS）技术制备了Ti-27Nb-17Ta-8Zr/HA系列复合材料。将具有良好力学性能、耐磨性和耐腐蚀性的医用钛合金（Ti-27Nb-17Ta-8Zr）与具有高生物活性和骨结合能力的羟基磷灰石（HA）生物活性陶瓷相结合。此外，还研究了不同HA含量复合材料的密度、微观结构演变、金属/陶瓷反应、力学行为、体外生物活性及其影响机制。研究结果表明，所有生物复合材料均由β-Ti固溶体、α-Ti和陶瓷相（TO、CaTiO、CaO、TiP）组成。随着HA含量的增加，复合材料的抗压强度和屈服强度呈现先增大、后减小、再缓慢增大的趋势。在模拟体液（SBF）中浸泡5天后，表面Ca、P等元素的沉积显著增加，而Ti、Nb、Ta、Zr等元素在基体中均匀分布，表明其具有良好的体外矿化能力，有利于成骨细胞的附着和生长。
